The role of Tmem263 in regulation of bone mass and strength

$1.73M USD

Funder	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Recipient Organization	Indiana University Indianapolis
Country	United States
Start Date	May 05, 2021
End Date	Apr 30, 2024
Duration	1,091 days
Number of Grantees	1
Roles	Principal Investigator
Data Source	NIH (US)
Grant ID	`10401449`

Grant Description

Our previous genome-wide association study identified 56 loci that were associated with bone mineral density (BMD) and fracture risk in men and women. One locus on chromosome 12q23.3 harboring the gene TMEM263 (Transmembrane protein 263) was strongly associated with hip BMD (p