Development and Evaluation of Portable Compendium of Psychophysical and Physiological Tests for Alzheimer's Disease and Related Dementias (ADRD)

ABSTRACT The Development and Evaluation of Portable Compendium of Psychophysical and Physiological Tests for Alzheimer’s Disease and Related Dementias (ADRD) is a project to develop an inexpensive, user-friendly, digital chemosensory-sensorimotor acquisition and processing device, with cross-cultural validity for home or

office use for automated (a) staging of severity of age-related cognitive decline, (b) prognostication of people with subjective cognitive impairment at risk for progressive neurodegenerative diseases, and (c) remote surveillance of trajectory in motor and chemosensory markers of ADRD progression in elderly populations.

Given that some decline in cognition is expected with advancing age, it is very challenging for elderly people to determine if their cognitive challenges are normal for age, or pathological. Similarly, our stakeholder survey of physicians who treat geriatric populations revealed that