California National Primate Research Center

PROJECT SUMMARY/ABSTRACT The California National Primate Research Center (CNPRC), located at the University of California, Davis, serves a range of NIH-supported investigators and collaborators nationwide. From inception through the current year, the CNPRC has been highly responsive to the research community by providing high quality animals, facilities,

tools, and services driven by the intellectual infrastructure of the Core Scientists in the service of the mission. The supplemental funds requested for Alteration and Renovation supports the NIH priorities for HIV-related research, and is within the scope of the parent award which includes the following Specific Aims: (1) Conduct

state-of-the-art research and scientifically contribute to the understanding and treatment of human disease with nonhuman primate models across the lifespan; (2) Provide exceptional nonhuman primate expertise and services to investigators at the local, regional, and national levels to advance NIH-supported research

excellence; (3) Mentor and train the next generation of translational investigators with nonhuman primate expertise and inform the public regarding the importance of the nonhuman primate model; and (4) Ensure the highest standards of responsible conduct of research and animal care. The base operating grant includes

Administrative Services, Alterations and Renovations, Colony Management Unit, Service Cores, Scientific Research Units (Cardiorespiratory Diseases, Infectious Diseases, Neuroscience and Behavior, and Reproductive Sciences and Regenerative Medicine), Outreach/Public Information Office, and the Pilot Research

Program. The CNPRC is committed to providing a wide range of research opportunities that maximize use of the nonhuman primate model to improve human health, including a focus on high priority topics in HIV/AIDS- related research such as the development of safe and effective vaccines and next-generation HIV therapies; the

conduct of research towards HIV cure; and cross-cutting areas of research and research training.