Maternal-Neonatal Registry (PAIR) Supplemental Funding

PROJECT SUMMARY The Eunice Kennedy Shriver NICHD Maternal-Fetal Medicine Units (MFMU) Network is a collaboration between fourteen Clinical Centers, the Data Coordinating Center (DCC) and the NICHD. Each clinical center is led by a Center Principal Investigator who is experienced in perinatal research and completion of both observational studies and clinical trials. Each clinical

center also has a full-time Research Coordinator dedicated only to MFMU Network studies. Robust clinical research infrastructure is maintained to ensure successful participation in all MFMU studies. The purpose of the Parent And Infant Registry (PAIR) is to collect linked baseline and outcome data for high-risk preterm pregnant persons and their infants. These data will be collected in a

uniform manner from medical records of pregnant persons and infants admitted to hospitals participating in the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units Network (MFMU) and Neonatal Research Network (NRN). The aims of this project are to:

Aim 1: Obtain screening information on all pregnant people hospitalized during periviable gestations. Aim 2: Describe outcomes of pregnant persons who deliver during the periviable window with linked neonatal outcomes. Aim 3: Capture data on periviable antepartum stillbirths, which are not currently captured in any

Network registry. Aim 4: Describe the incidence, timing, and outcomes of periviable antenatal counseling. The funding providing by this administrative supplement will allow for an extension of the data collection period, thus increasing the sample size of the pilot cohort.