Deciphering the effects on the tumor microenvironment of Neo-X-Prime bispecific antibodies

Purpose and goal:

The objective of the proposed project was to implement recent scientific and technological breakthroughs in clinical translational development within Alligator Bioscience and thereby strengthen a strategically important area. To achieve this, the MSCA follow has: -Set up in vivo models and experimental protocols

-Performed RNA -sequencing and data analysis in our in vivo models and targets cancer indications.

The results from these studies are very promising and supports the development of Alligators drug candidates targeting CD40. Expected results and effects:

The results from the projects exceeded expectations and the results will be published in scientific journals (manuscript submitted) and at two scientific meeting during the fall in September and December. The project has resulted in transfer of important know-how in the data science field to the company and the MSCA fellow now has a permanent position at the company.

Approach and implementation:

The project achieved the purpose with the grant in a very efficient manner and we appreciate the opportunity to very effectively transfer important knowledge.