Design and bench testing of biodegradable cages for spinal fusion

Purpose and goal: ** Denna text är maskinöversatt **

The aim is to design Mg alloy spinal implants using topology optimization and to verify its function in mechanical tests. This has previously been successfully done by the MSCA grantee (Salim Ghandour) for titanium spinal fusion implants.

Inossia AB, who is active in the commercialization of new products for an aging spine, aims to capture and retain Salim´s excellence in the field. The objective is to develop a prototype for a new type of spinal implant for spinal fusion where the implant must both be initially weight-bearing and degradable over time.

Expected results and effects:

The current project is within Inossia AB’s expertise and will provide a good start for potential commercialisation in the long-term. The commercialization of fusion implants made from Mg alloys could revolutionize spinal procedures, but also constitute the starting point for solutions for other surgeries such as enabling healing of large, complex bone defects, the elimination of revision surgery and enabling treatment of growing individuals. This would constitute a true paradigm shift in the orthopaedic and spine industry.

Approach and implementation:

The project is organized into four work packages, each focusing on specific aspects of the development process while allowing for overlapping activities and continuous progress. WP1. Project management (Dr Nilsson) WP2. Degradable fusion cage optimization (Mr Ghandour) WP3. Optimization of additive manufacturing process (Mr Ghandour)

WP4: Mechanical validation (Mr Ghandour)