E!5245, ExoCast®DFU, Spirotronic AB

Purpose and goal:

The project will investigate, develop and validate the feasibility of a new wearable orthopedic boot cast for the treatment of chronic wounds in the "diabetic foot".

The boot will consist of a rigid outer shell reaching just below the knee, and be provided with a lining that surrounds and supports the entire foot and lower leg. The boot will have a sensor array inside that records parameters related to wound healing. Expected results and effects: The project will generate the following results:

1 - A rigid polymer boot that encases the foot and leg up to the knee. 2 - An elastomeric pressure off-loading lining inside the boot. 3 - A sensor array inside the boot that monitors physical real-time conditions. 4 - A data collection and transmission unit 5 - A mobile app that communicates with the sensors and displays physiological values.

6 - A secure database for storing readings on a per-patient basis. 7 - A method for the manufacture of the boot using additive manufacturing technology. Approach and implementation: Prototal: Research, development and manufacture of the rigid polymer shell and a pressure relief liner placed inside the boot using additive manufacturing techniques.

Spirotronic: Research and development of a sensor array placed inside the boot that monitors

real-time physical conditions. Design of an electronics module that collects sensor data and enables wireless transfer of data from the boot to a mobile app. Cubist: Research and development of a mobile app that communicates with the sensors and displays physiological values.