Robust manufacturable controller and miniaturized electronics for Total Artificial Hearts

Purpose and goal:

The objective of the project is to use the new cardiovascular simulator developed in the previous project to further evaluate the artificial heart, develop the clinical controller for robust manufacturing, and take the first development steps for a smaller sequel of the artificial heart for patients of smaller body size, mainly women.

Expected results and effects:

Comparative data between Realheart TAH and the market-leading competitor to be used for marketing purposes and to increase interest in the company among investors; controller that is more optimized for manufacturing; evaluation of the performance of components critical to size reduction; developed strategy to miniaturize the electronics.

Approach and implementation:

Realheart TAH and competing product are tested in the new cardiovascular simulator (WP1). In parallel, MINIheart is computer simulated in different digital twins to identify product size and cardiac output (WP2). Then the physiological controller is evaluated and steps to increase robustness and manufacturability are applied (WP3).

Then there is parallel testing of new mechanical components critical for size reduction (WP4) and strategies to miniaturize the electronics (WP5). Project management, IP, equality work, dissemination of results are continuous throughout project.