RADAR-Base: Democratising Access to Remote Monitoring Infrastructure for Research and Decentralised Clinical Trials

Mobile health (mHealth) has transformed the potential for collecting real- world data remotely and objectively for research and clinical applications.

Widespread adoption of mobile phones and wearable sensors has been the catalyst, allowing passive measurement of an expanding array of parameters, including behavioural like cognition, mobility, sleep, and sociability, and physiological such as activity, heart rate, glucose, and blood pressure.

Simultaneously, actively generated data, e.g. patient-reported measures, can be collected through app-delivered questionnaires and digital assessments. By harnessing these data streams in one place, researchers gain deeper insights into disease. Remote data collection poses a significant challenge, particularly for independent researchers.

We developed RADAR-Base, a scalable, real-time streaming and analytics off-the-shelf platform for digital biomarkers.

The platform has an active and rapidly growing international community spanning academia and industry, with use cases in mental health (e.g. depression, ADHD, psychosis), physical health (e.g. heart disease, epilepsy, diabetes), and infectious disease (e.g. COVID-19).

This proposal will resource the growth and engagement of our community, supporting a sustainable service model and the development of critical functionality required for the next phase of RADAR-base. Together, this will provide a step change in open-source mobile health capabilities to the global community.