A prospective randomised trial comparing radiofrequency ablation With laparoscopic Adrenalectomy as an alternatiVE treatment for unilateral primary aldosteronism (WAVE)

£49.79M GBP

Funder	British Heart Foundation
Recipient Organization	Queen Mary, Universityersity of London
Country	United Kingdom
Start Date	Dec 01, 2022
End Date	Nov 30, 2026
Duration	1,460 days
Number of Grantees	1
Roles	Award Holder
Data Source	Europe PMC
Grant ID	`CS/F/20/190025`

Grant Description

Of 12M people in the UK with hypertension, 5-10% have primary aldosteronism (PA).

Cardiac morbidity (atrial fibrillation, heart failure) in PA patients is twice that in essential hypertension; this combination of prevalence and penalty mandates detection, investigation and treatment of PA. ~50% of cases are caused by a single, potentially resectable aldosterone producing adenoma (APA).

At present