NIHR Barts BRC

The Barts BRC Scientific Plan (written with our patients) Our vision is to detect disease early, carefully sub-divide patients into groups and provide effective individualised treatments.

We will use real-world data to identify different patient groups that will enable us to better understand disease so we can develop more precise treatments.

Our goal is to transform outcomes in heart disease, arthritis, and cancer by: Rapid diagnosis of rare abnormal heartbeats to reduce sudden death, then screen and prevent disease in surviving relatives. Enhanced detection and monitoring in cancer via innovative tests that enable earlier individualised treatment.

Improve risk assessment through the development and testing of new genetic risk scores to improve prevention of heart disease, arthritis, and cancer. Testing new cardiovascular devices that will lead to new device treatments and increase benefits for patients. Optimising treatments using information from tissue samples to select tailored treatments for arthritis and cancer.

With today's advances in technology, we can harness data from many sources e.g.: Mobile phones with healthcare records build a more accurate “digital” picture of patient health; Adding the latest genetic studies to test the role of individualised healthcare We will create specific therapies and devices tailored to patient needs through earlier diagnoses and disease detection.

We are ready for this challenge: Our partnership combines the strength of Barts Health NHS Trust, the second largest UK healthcare provider, with Queen Mary University of London (QM), a top UK university; and partners St George's University of London and NHS Trust Together, we serve a richly diverse community of 2.5 million people.

We have the unique opportunity to bring individualised healthcare to those suffering disease in East London.

We led the 100,000 Genomes Project: Helped us to understand how a person s genetic makeup can diagnose rare genetic diseases and provide individualised care for 25% of cancer patients; this transformed the NHS in 6-years.

From this internationally renowned foundation, we will spread digital individualised healthcare to rare and common heart diseases, arthritis, and cancer. We will bring major patient benefits throughout our diverse community.

Our digital health research is: Combining health records from primary care and our hospitals: Enabling clinical data, study of disease and scans on 2.5 million people will extend London-wide to 6-million people (The Covid pandemic showed mobile technologies helped patients). Enabling us to obtain information in 60 languages, encouraging under-served communities to participate in research.

Our personalised healthcare research: Adds state-of-the-art genetic assessment at tissue and cell levels that will lead to ground-breaking treatments for patients. Is paving the way for new diagnoses, early disease detection, and personalised therapy.

Outcomes: We will: Develop personalised healthcare for our diverse communities Provide early diagnoses in specific disease areas, and Create a springboard for ground-breaking treatments and devices.

With the Department of Health and Social Care (£80m), develop 1 million square feet of land in Whitechapel for Life Sciences and invest £85m in a new digital individualised healthcare centre Impact: We will create the NHS of the future from this BRC