Generation differences in determinants of cognitive aging: Comparisons of five population-based representative Swedish cohorts born 44-years apart and followed from age 70 on multiple occasions

Studies show large birth cohort differences in cognitive aging. In terms of level, onset of decline, and rate of change. Studies also reveal multiple interacting factors accounting for observed individual differences.

We know little about how the relative importance of these factors differ across generations—where some become more/less important as determinant of cognitive aging.

Reasons for current absence of knowledge is due to lack of relevant data, which is difficult to obtain since it requires multiple follow-ups of cohort born decades apart. The H70 is one of few studies that allows such comparisons.

The ongoing project, initiated in 1971, includes multiple follow-ups, on cognitive, health, lifestyle, and demographic factors from age 70 across five population-based cohorts born in 1901, 1906, 1923, 1930, and 1944.

In the proposed project, we take advantage of collected data and model time trends across cohorts in effects of health-related, lifestyle, and demographic factors on individual differences in cognitive aging. We use growth curve modelling techniques and aim to replicate findings within NEAR.

Project outcomes contribute to: 1) a better understanding of factors leading to cognitive decline; 2) improved public health recommendations; 3) predictions concerning relative importance of determinants for cognitive aging and dementia risk in future populations. This information is essential for informed decision making concerning health and welfare in greying societies.