Early detection of bladder cancer in Yorkshire: Feasibility assessments for implementing a targeted study in populations with high disease specific mortality risk

£15.02M GBP

Funder	Yorkshire Cancer Research
Recipient Organization	University of Sheffield
Country	United Kingdom
Start Date	May 01, 2021
End Date	Apr 30, 2024
Duration	1,095 days
Number of Grantees	1
Roles	Award Holder
Data Source	Europe PMC
Grant ID	`RA/2019/R1/004`

Grant Description

We will undertake the feasibility steps for a comprehensive early detection programme for bladder cancer across Yorkshire. We will combine home urine dipstick self-testing with community early detection clinics.

We will examine 3 cohorts in parallel: - Cohort 1: 2,000 Research engaged male and female participants of the Yorkshire Lung Screening Trial (YLST) will undertake haematuria home testing. - Cohort 2 : 3,000 males will be randomsied to self-test for either haematuria or glycosuira using a reveal/conceal design - Cohort 3: NICE 2WW patients: Urology assessments (including cystoscopy, cytology and ultrasound) in 500 male and female patients within the NHS