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99,167 grants found
Showing 95,741 – 95,760 of 99,167 grants
Psychosocial Risk in Young Survivors of Early Onset Pediatric Cancer: The Role of Physical and Neurocognitive Late Effects
Despite increased survival,1 over two-thirds of children with cancer experience late effects, such as secondary cancers, sensorimotor deficits, and neurocognitive impairment.2,3 Ps...
Molecular mechanisms underlying morphogenesis of the tectorial membrane
PROJECT SUMMARY/ABSTRACT The tectorial membrane (TM) is an extracellular matrix (ECM) that lies over the organ of Corti. The TM plays important roles in frequency selection, propag...
Vitamin K: Body Pools and Function in Breast Cancer
PROJECT SUMMARY/ABSTRACT This proposal focuses on the divergent effects of the two major dietary forms of vitamin K on breast cancer. K vitamins act as cofactors for gamma-glutamyl...
Psychosocial Risk in Young Survivors of Early Onset Pediatric Cancer: The Role of Physical and Neurocognitive Late Effects
Despite increased survival,1 over two-thirds of children with cancer experience late effects, such as secondary cancers, sensorimotor deficits, and neurocognitive impairment.2,3 Ps...
Diversity Supplement: Investigating Epithelial Mesenchymal Plasticity in Crainbow mice
Abstract Please see Abstract included in Research Plan document.
Molecular mechanisms underlying morphogenesis of the tectorial membrane
PROJECT SUMMARY/ABSTRACT The tectorial membrane (TM) is an extracellular matrix (ECM) that lies over the organ of Corti. The TM plays important roles in frequency selection, propag...
Visualizing tumor heterogeneity in an immune intact and autochthonous mouse model of breast cancer
ABSTRACT Genetically modified mouse models of breast cancer have been used for decades as premier basic science tools for mechanistic discovery. However, the successful implementat...
Development of microRNA (miR)-based cell-targeted polymeric nanoparticles for myeloma therapy
Project Abstract Multiple myeloma (MM), a cancer of plasma cells that colonize the bone marrow (BM), remains incurable despite the use of new promising treatment modalities. This i...
JAML-CAR regulation of adipose tissue homeostasis
Obesity and obesity-related diseases are at epidemic levels globally (WHO).Obesity-associated inflammation has recently received much attention due to its devastating consequences...
Psychosocial Risk in Young Survivors of Early Onset Pediatric Cancer: The Role of Physical and Neurocognitive Late Effects
Despite increased survival,1 over two-thirds of children with cancer experience late effects, such as secondary cancers, sensorimotor deficits, and neurocognitive impairment.2,3 Ps...
Psychosocial Risk in Young Survivors of Early Onset Pediatric Cancer: The Role of Physical and Neurocognitive Late Effects
Despite increased survival,1 over two-thirds of children with cancer experience late effects, such as secondary cancers, sensorimotor deficits, and neurocognitive impairment.2,3 Ps...
Vitamin K: Body Pools and Function in Breast Cancer
PROJECT SUMMARY/ABSTRACT This proposal focuses on the divergent effects of the two major dietary forms of vitamin K on breast cancer. K vitamins act as cofactors for gamma-glutamyl...
Visualizing tumor heterogeneity in an immune intact and autochthonous mouse model of breast cancer
Abstract Please see Abstract included in Research Plan document.
Integrated radiomic and liquid biopsy monitoring in SWOG S1802: A phase 3 therapeutic trial for metastatic prostate cancer
Abstract Prostate cancer (PC) afflicts more men in the U.S. than any other malignancy and is the second leading cause of cancer death in this population. Recently, new therapies ha...
Molecular mechanisms underlying morphogenesis of the tectorial membrane
PROJECT SUMMARY/ABSTRACT The tectorial membrane (TM) is an extracellular matrix (ECM) that lies over the organ of Corti. The TM plays important roles in frequency selection, propag...
Visualizing tumor heterogeneity in an immune intact and autochthonous mouse model of breast cancer
ABSTRACT Genetically modified mouse models of breast cancer have been used for decades as premier basic science tools for mechanistic discovery. However, the successful implementat...
Vitamin K: Body Pools and Function in Breast Cancer
PROJECT SUMMARY/ABSTRACT This proposal focuses on the divergent effects of the two major dietary forms of vitamin K on breast cancer. K vitamins act as cofactors for gamma-glutamyl...
Development of microRNA (miR)-based cell-targeted polymeric nanoparticles for myeloma therapy
Project Abstract Multiple myeloma (MM), a cancer of plasma cells that colonize the bone marrow (BM), remains incurable despite the use of new promising treatment modalities. This i...
Psychosocial Risk in Young Survivors of Early Onset Pediatric Cancer: The Role of Physical and Neurocognitive Late Effects
Despite increased survival,1 over two-thirds of children with cancer experience late effects, such as secondary cancers, sensorimotor deficits, and neurocognitive impairment.2,3 Ps...
Psychosocial Risk in Young Survivors of Early Onset Pediatric Cancer: The Role of Physical and Neurocognitive Late Effects
Despite increased survival,1 over two-thirds of children with cancer experience late effects, such as secondary cancers, sensorimotor deficits, and neurocognitive impairment.2,3 Ps...