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15,626 grants found
Showing 7,101 – 7,120 of 15,626 grants
Neuronal network analysis of somatosensory circuits – regulation and transmission of pain and itch
Persistent pain and itch affect a large part of the population.Persistent itch is a major symptom in conditions such as atopic dermatitis and psoriasis, where itch is ranked as one...
Development, relapse and treatment of malignant pediatric brain tumors
Despite intensive research, better surgery and more precise radiotherapy, cancer and in particular brain tumors is still the main cause of death in children under 15. Medulloblasto...
Fair business development for Non-Timber Forest Products based on local knowledge. Tamarindus in Kenya.
Many African tree species provide products that can contribute to food, medicine, and income to rural low-income households. The development of such tree species can also be an inc...
Impact of physiological aging and redox homeostasis on lung cancer progression
During tumorigenesis, cancer cells must overcome barriers of oxidative stress due to increasing levels of reactive oxygen species (ROS).Following our initial findings, a plethora o...
Inkretinsystemets inverkan på hjärt-kärlsjukdom och cancer
The core of this research proposal are the applicant ́s novel findings from two large prospective cohorts showing that elevated levels of glucose-dependent insulinotropic polypepti...
Plasmodiophora brassicae: Infection machinery and host interactions
We have established extensive knowledge on plant defence mechanisms and genomes of pathogens during the last two decades. The latter being the starting point for many molecular int...
MITOCHONDRIAL GENE EXPRESSION: BASIC ASPECTS AND CONNECTION TO DISEASE
The human mitochondrial genome (mtDNA) is expressed and maintained by enzymatic machineries that are distinct from those used for these processes in the nucleus. These machineries...
Exposure to contaminants via food and drinking water – potentially overlooked modifiable risk factors in chronic disease development
The hypothesis we will test is whether the prevalent exposure to the most widespread and persistent contaminants in food and drinking water compromise our health and contribute to...
A test to assess chemical persistence in the natural environment
The intention of the European Commission to include persistent & mobile chemicals among substances of very high concern is one example of the increasing importance of persisten...
Sustaining marine biodiversity under climate change: Spatial planning to maximise the future connectivity of the Baltic Sea marine protected area network
Climate change and anthropogenic disturbances cause major losses in biodiversity and threaten important ecosystem services.Marine protected areas (MPAs) have become a key component...
The role of the prenatal environment in setting the epigenetic clock (Epi-Clock)
How we age, and how fast, differs considerably between individuals.This deviation between apparent age and chronological age is often referred to as “biological age” and until rece...
Mens higher cancer risk - the role of androgen receptor inactivation by environmental carcinogens
Men have higher cancer incidences than women.Lifetime risk for men is 50% and for women 30% and an incidence quote of 1.8 for men/women has been shown for cancer in non-sex organs....
Resolving TRP channel intrinsic sensory properties at the molecular level
The involvement of transient receptor potential (TRP) ion channels as molecular sensors in chemo-, thermo- and mechanosensensory neuronal and secretory cell signaling has opened-up...
The Genetics of Inflammation
Autoimmune diseases are highly heterogeneous.Heterogeneity is not limited to the clinical presentation, but also to differences in the molecular and cellular mechanisms affecting t...
A systems biology approach to identify host molecular signatures of genital Candida albicans infection – implications for sexual HIV transmission
Background: The fungal infection C. albicans is prevalent in the female genital mucosa and can cause symtomatic vulvovaginal candidiasis with intense mucosal inflammation.Genital i...
DigitalWell Incubator
Purpose and goal: ** Denna text är maskinöversatt **DigitalWell GovTech Incubator will accelerate the development of healthtech companies where the public sector plays a central ro...
Mapping the heterogeneity of inherited risk factors for Alzheimer’s Disease
The aim of this 4-year project is to map the genetic heterogeneities of Alzheimer’s Disease (AD), to accelerate the development of personalized treatments.A novel approach will be...
Quantitative fingerprinting of chemical contaminants in pollinating insects – Green unified chromatography and advanced detection techniques supported by machine learning
Pollinating insects are exposed to chemical products in the environment, both in agricultural areas (pesticides) and in private gardens and other urban areas (chemicals for private...
Role of galectin-1 in obesity-driven type 2 diabetes
Our overall aim is to better understand the pathophysiology of obesity-driven type 2 diabetes that will help us towards new strategies for prevention and treatment of the disease.I...
Will the microbial filter prevent methane emissions from Baltic Sea coasts in a warmer future?
Anaerobic oxidation of methane via sulphate reduction is the main microbial process preventing the seafloor release of large quantities of CH4 from sediment to the water column and...