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15,626 grants found
Showing 7,221 – 7,240 of 15,626 grants
Retinoic acid-based technologies for cell replacement therapy of Parkinson’s disease
Stem cell-based cell replacement therapies have strong potential to provide a restorative treatment for Parkinson’s disease (PD), affecting ~10 million people worldwide and prevale...
Aerobic exercise to minimise cardiovascular disease risk in lymphoma survivors - The LYMfit multicenter randomized controlled trial
Lymphoma treatment includes high doses of chemotherapy potentially toxic to the heart.There is a two to three-fold increased risk of cardiovascular disease (CVD) among lymphoma sur...
Sustainable structural design and construction through updated design loads
The purpose of the project is to evaluate how sustainability can be increased in design and construction by updating the current levels of imposed loads and the related design mode...
Dissecting molecular interplay between leukemic stem cells and their niche in acute and chronic myeloid leukemia
The main challenge for treating leukemias is therapy resistance, resulting in treatment failure and relapse, which ultimately leads to death. Consequently, there is an urgent need...
Eco-friendly transparent wood for a brighter future
The purpose of the project is to investigate scalable production methods for transparent wood, and related material issues. The most important challenge is to avoid optical defects...
Morbidity among older women and men in paid work when aged 66-70 or >70 years, among all and specifically for the health and social care sector; prospective population-based cohort studies
The current demographic changes, with higher proportions of older people in the population and the workforce, imply challenges for healthcare, social care, public health and social...
Development of long-lived tumor homing NK cells to induce durable leukemia remission: exploration of novel chimeric cytokine signaling receptors and JAK-STAT signaling CARs
Adoptive infusion of natural killer (NK) cells can induce remission in 30-50% of patients with advanced acute myeloid leukemia (AML).Poor persistence and tumor homing of the NK cel...
Fluorocarbon pollutants in water. Molecular insights into removal strategies
Fluorinated surfactants, which pertain to the group of per- and poly-fluoroalkyl substances (PFAS), were originally thought to be innocuous, but are now recognized as highly persis...
Targeting senescent adipocytes to treat tumour progression and metastasis in humans
Excess adipose tissue has been shown to increase the risk for many types of cancers and is associated with poor cancer outcomes. Obesity is increasing in epidemic proportions world...
Identification of a therapeutic strategy to reduce fibrotic scarring and promote central nervous system repair.
Damage to the adult mammalian central nervous system (CNS) often leads to persistent functional deficits.The establishment of these deficits is associated with scar tissue that for...
Inhibitory interneurons in neuronal circuits for emotion and cognition
The purpose is to investigate how neuronal circuit activity give rise to behaviour and mental function.Such studies require insight into the participating neuronal types, their loc...
Direct Mineralization of Atmospheric CO2 by Enhanced Weathering
Rock weathering could be used as an effective negative CO2 emission technology to help solve the climate crisis.This process could be sped up by orders of magnitudes in an industri...
Cellular heterogeneity of human glioblastoma
Recent advances in single-cell biology have enabled very large-scale mapping of cell types and cell states.Emerging brain cell atlases now provide unprecedented access to the molec...
Betnings tolleranta träd
Ungulate browsing results in billions in losses to the forest sector annually and is the main hindrance to the establishment of broadleaves in large areas.The project focuses on th...
Precision medicine tools for the neglected tropical disease visceral leishmaniasis
Visceral leishmaniasis is a fatal neglected tropical parasitic disease, mainly affecting the poorest of the poor, particularly in Eastern Africa. No good, safe, affordable and easy...
Combining semiochemicals with ecological intensification to harness aphid biocontrol in various cropping settings.
Aphids are serious agricultural pests, colonizing more than a quarter of the existing plant species.Control strategies unfortunately are highly dependent on chemical pesticides, wi...
Control of body weight by specialized brain-adipose loop neurons
Obesity is the most common metabolic disease in the developed world, and its comorbidities are leading causes of premature death and major economic burdens.As current therapeutic i...
Climate emotions and affective dilemmas: A psychological and philosophical study of their normative principles and the public perceptions
Climate emotions have recently become a matter of normative scrutiny, including questions about how oneself or others ought to feel in the face of climate change (as opposed to how...
The impact metabolic health on osteoarthritis, from disease development to joint replacement.
Osteoarthritis (OA) is among the main and fastest-growing causes of disability worldwide.Moreover, more than 80% of OA patients suffer from other conditions including metabolic dis...
Improving estimates of climate-driven body size changes and range shifts in fishes by accounting for fine-scale spatial heterogeneity
Fish are generally predicted to “shrink” (grow faster but attain smaller adult body sizes) when the oceans warm.However, observations from natural systems show high variability amo...