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15,626 grants found
Showing 7,241 – 7,260 of 15,626 grants
Genome-scale multi-OMICS in primary sclerosing cholangitis and cholangiocarcinoma for personalized medicine
Scandinavia is the part of the world where primary sclerosing cholangitis (PSC) is most frequent. The etiology is unknown which limits the development of targeted therapy. There is...
Long noncoding RNAs: Understanding their nexus with oncogenic and tumor suppressor pathways
Despite advances in oncology, our ability to cure cancer stands at unsatisfactory rate and still requires developing new therapies.Recent evidence suggests that long noncoding RNAs...
Symbiont-driven disorders in zooplankton reproduction (iCard)
Alterations in zooplankton communities are occurring on a global scale, but we still have a limited understanding of their drivers.Despite the widely observed linkage between decre...
Selective removal of water contaminants of emerging concern through in-situ molecular mechanistic understanding
Ensuring the availability of clean water is an essential global challenge. A significant fraction of the world’s population is at risk of water scarcity or insecurity.Water plays a...
FOOD-INDUCED DUODENAL IMMUNE ACTIVATION: SYMPTOM TRIGGER AND THERAPEUTIC TARGET IN FUNCTIONAL DYSPEPSIA
Functional dyspepsia (FD) affects 7.2% of the adult population and has a significant impact on quality of life.Patients present with symptoms in the epigastrium, which include earl...
Studies of structural chromosome rearrangements to identify genes and cellular mechanisms involved in congenital brain disorders
The project is focused on the detailed study of structural genomic variants (SVs).Such genetic mutations are in fact alterations in the DNA molecule structure and include copy numb...
Dynamic Sow? Improved animal welfare and production in systems with dynamic sow groups and electronic sow feeders (ESFs) through automatic surveillance and strategies for introduction of sows
Group housing systems for pregnant sows are under development, driven by transition from individual stalls to group housing in the EU.Group housing has animal welfare benefits over...
Method for extraction of bismuth and antimony, and removal of arsenic from industrial residue
The aim is to develop efficient methods for extracting copper, bismuth and antimony, and removing arsenic in a stable phase rendered harmless for the environment.This harmonises wi...
Connecting mitochondrial methylation potential to cellular dysfunction and disease
Mitochondria form a central hub in cellular metabolism, with a vast number of different metabolic pathways relying on their function.Dysfunction of this organelle is increasingly l...
Entrepreneurial Human Capital: Implications for firms’ resilience and sustainability in rural and urban regions
This project focuses on how employees’ previous experiences of entrepreneurship affect firms´ productivity, adaptability, and innovation capacity. The importance of flexible and tr...
Increase animal welfare and quality of life in dogs with tumors as we search for the silver bullet for cancer
Cancer is the single most common cause of death in dogs. It also affects the quality of life/animal welfare of many dogs.Thus, there are reasons to find better diagnostics and new...
Precision therapy of type 2 diabetes
Type 2 diabetes (T2D) is an escalating health problem of enormous proportions. Clinical guidelines emphasise the need for personalized treatment to stop disease progression.However...
Establish collaboration to develop a digital intervention to promote health behaviors among young adults with intellectual disability
Young adults with intellectual disability (ID) have more sedentary lifestyle compared to young adults in the general population.There is a lack of evidence-based knowledge on how p...
Niche geometry in stem cell regulation and ageing
Tissue renewal by adult stem cells is regulated by a multitude of cell intrinsic and extrinsic mechanism, which jointly guide decisions between two cell fates - stem cell self-rene...
Follow-up of girls placed in institutional out-of-home care during 1993 and 2006
How are girls placed in residential out-of-home care faring in adulthood? According to previous research, not so good. High levels of mental illness, psychosocial problems, and sub...
With and for older people – preventing health deterioration through a co-research model
Prevention of health deterioration among older people is considered a priority in Sweden to ameliorate the increased demand for health and care services that is anticipated to acco...
CROSSTALKS BETWEEN IMMUNITY, DNA REPAIR, AND THE MICROBIOTA – NEW WINDOWS FOR FUTURE THERAPIES?
The immune system and the DNA repair system are fundamental for life. Hence, defects in these systems lie at the core of most health conditions. Much of our current understanding o...
Dissecting the genetic basis of complex diseases via the stratified high-definition likelihood method
Heritability and genetic correlation are central parameters for understanding the genetic architecture of complex diseases. It is essential to assess the enrichment of these parame...
“Practicing what you preach” – Are evidence-based strategies for implementation employed in efforts seeking to enhance an evidence-based practice in social services?
´Knowledge governance’ as a means for strengthening the equity, effectiveness and quality of social services has been developed in Sweden over the last decade.As part of this effor...
Implementing a South African social innovation for maternal peer support in low resource settings in Sweden – an evaluation of the Mentor Mother program
Maternal and child health in Sweden is generally good, but unequal, largely due to the substantial differences in socio-economic status between children growing up in areas with a...