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15,626 grants found
Showing 7,721 – 7,740 of 15,626 grants
Refining neurovascular in vitro models
All systemically administrated drugs need to be evaluated for central nervous systems (CNS) penetration and adverse effects.Unfortunately, and especially for new drug modalities, t...
Long-term mechanical behavior of dowel connections in timber structures as the basis for an extended service life and reuse
The project aims at gaining more knowledge on the long-term behavior of dowel connections, as the key factor for an efficient connection design and as basis for an extended service...
Cost effective biodiversity monitoring at small spatial scales
Long-term monitoring is an important tool for assessing how biodiversity is changing as a consequence anthropogenic effects on the environment, such as land-use change and climate...
Forging systemic coherence: Transformative portfolio approach for urban transition governance
The proposal addresses a crucial step of going beyond fragmented transition experiments and linking them collectively with transformative change. With this, it aims to contribute t...
SoundMIND – effects of noise on cognition and mental health
Traffic noise is an environmental exposure of growing concern with mounting evidence of serious adverse health effects.At least one in five Europeans (113 million people) are expos...
Development of an in vitro screening platform for discovery of novel pharmaceuticals for bone metastasis to limit animal use in cancer research.
Prostate and breast cancer are among the top five most prevalent types of cancer and are responsible for 70% of all skeletal metastasis.This is fatal as no currently available drug...
Municipal governance and changing local rental markets: medium-sized municipalities’ strategies when meeting residential property investors
Sweden’s municipalities increasingly integrate and collaborate with private rental actors in housing production and urban planning.Earlier research has shown that these actors’ hou...
Development of a bio-based process to produce platform chemicals from food production waste
Many industrially relevant chemicals are produced from fossil fuels in hazardous processes, including some that emit substantial greenhouse gases.Bio-based processes can instead us...
Mechanobiology of cardiac regeneration: a molecular approach
Adult heart is one of the least regenerative organs in the human body, with substantial fibrotic scarring in response to tissue damage. In contrast, aquatic salamanders, such as th...
Defining the role of GPR34, GPR65 and GPR183 as therapeutic targets in blood cancers
G-protein-coupled receptors (GPCRs) constitute 30% of all drug targets and are often overexpressed and mutated in cancer, including haematological disorders. There is an immediate...
Deep Optical Imaging of the Breast, DOIT-B
Optical imaging (OI) encompasses a range of techniques using near-infrared and visible light to generate molecular, morphologic, and functional information, examining e.g. absorpti...
Planning for sustainable development. Large scale investments and societal transformation
Several large investments in northern Sweden are associated with a green transformation expected to contribute to both climate change adaptation and sustainable growth.The purpose...
Holistic assessment and optimisation of packaging-free concepts for food retailing
Packaging for food is often perceived as an environmental burden, thus triggering the development of retail concepts that do not use single-use consumer packaging. These concepts u...
EvoMaps: How cellular ecosystems drive early breast cancer evolution
Breast cancer develops from atypical hyperplasia, through ductal carcinoma in situ (DCIS) to invasive carcinoma. However, only few DCIS have potential to progress.Since underlying...
Raising seafood self-sufficiency aided by agricultural side streams -SEASIDE
Sweden exports nearly 85% of all its fish raw materials for fodder meal/oil production -mainly herring and sprat- while we at the same time import 74% of all consumed seafood.The r...
Mapping human dopamine neuron diversity at single-cell resolution for enhanced stem cell therapy in Parkinson´s Disease
Midbrain dopamine (DA) neurons are a heterogeneous group of cells mainly comprising two major subgroups: A9 neurons control motor functions and are primarily degenerated in Parkins...
Epidermal Bioelectronics for Infection Monitoring in Human Skin Wound
One-fifth of Sweden’s population is affected by slow-healing wounds, and the number is rapidly growing. In Sweden, 2.5 billion SEK is spent on treating chronic wounds annually.Nota...
Nocturnal formation and evolution of organic nitrates and their night-to-day transition in urban and rural areas
Organic nitrates (ONs), as an important reservoir of nitrogen oxides (NOx), play a crucial role for secondary organic aerosol (SOA) and tropospheric ozone (O3) production.Our under...
Deciphering the co-effects of response to climate changes and perfluoroalkyl substances on the zebrafish
One of the major challenges of our century is environmental sustainability. Indeed, anthropic activities are threatening ecosystems’ balance and biodiversity survival. Assessing th...
Calcium signaling during neural development in mental disorders
The overall aim of our research is to determine pathophysiological mechanisms during neural development in the context of severe mental disorders, including bipolar disorder (BD).B...