Browse All Grants
15,626 grants found
Showing 7,761 – 7,780 of 15,626 grants
Molecular dissection of neural circuit assembly
The human genome contains several thousand genes that encode the brain’s connectome, a precise assembly of neural connections with trillions of synapses. How is genomic information...
Breeding oilseed rape (Brassica napus L.) for durable disease resistance and improved seed cake nutritional quality
Oilseed rape (OSR) is the most important oilseed crop in Sweden.Glucosinolates (GSLs) play important roles in defense against the most devastating soil-borne fungal pathogens like...
Assessment of acute respiratory and cardiovascular health effects due to biomass smoke exposure in the Brazilian Amazon
Biomass burning is a global concern in terms of climate change, biological diversity, and health hazards. Globally, ca 3 billion people are exposed to biomass particulate matter (P...
From sensitive to robust athlete – exploring the opportunities of genomic selection to help dairy cows cope with increasing temperatures
Dairy cows are sensitive athletes, bred for efficient metabolism and high production under optimal conditions.This makes them susceptible to heat stress, which has negative impact...
Therapeutic landscapes beyond the lush season: extending the well-being benefits of urban green and blue spaces through outdoor leisure
Mental health has become an increasing problem in the European Union and a similar trend is observed in Sweden.While there is well-documented evidence that urban nature (green/blue...
AMIME: Artificial intelligence-assisted plankton Monitoring with Imaging flow cytometry and MEtabarcoding
Single-celled eukaryotic plankton (protists) form the productive base of marine ecosystems and are key drivers of global biogeochemical cycles of carbon and nutrients.Consequently,...
Targeting of EpCAM using DARPin molecules for theranostics of ovarian cancer
Efficient treatment of disseminated ovarian cancer (OC) remains an unmet clinical need.Targeted delivery of cytotoxic payload (drugs or toxins) selectively to tumor cells while spa...
The metabolomics imprint of controlled modification of carbohydrate quality elucidates long-term impact on cardiometabolic disease risk and facilitates precision prevention approaches
The glycemic response to carbohydrate (CHO) intake varies, depending on the dietary CHO quality and individual metabolic predisposition.However, the long-term metabolic adaptation...
Delineating the systemic landscape and novel drug targets ín cutaneous melanoma for improved clinical decision-making
Immune checkpoint inhibitors and targeted therapies have improved the outcome for metastatic cutaneous melanoma (CM) patients.The histopathological and molecular characterization o...
Improving harmful algal bloom predictions in the Middle East: how submesoscale physics disrupt food and water security.
Coastal regions of the Arabian Sea frequently experience HABs, disrupting food and water security in surrounding countries.While large-scale processes triggering blooms off-shore a...
The neurocircuitry of incubation of relapse to opioid seeking
The main challenge in opioid addiction treatment is high relapse rates.To date, preclinical studies of opioid relapse are limited and have used animal models in which the abstinenc...
Novel strategies to overcome resistance to p53 reactivation in brain tumors
Over 60% of high-grade gliomas (HGGs) retain functional p53 and can benefit from treatment with MDM2 inhibitors.In the clinical setting, and unlike other cancers, lack of response...
Intake of vitamin D - strategies for health and climate sustainability
Climate change is a global threat and food production is targeted as the largest cause. Thus, a transition towards a more plant-based diet with lower climate impact is warranted.Fo...
AI-based Risk Stratification and Management of Preterm Infants
Preterm birth is the leading cause of neonatal mortality and morbidity worldwide.Although recent improvements in neonatal intensive care have increased the survival rates of premat...
Impaired creatine metabolism in white adipocytes of obese subjects promotes insulin resistance and type-2 diabetes
Besides their capacity to store lipids and secrete hormones, we recently identified white adipocytes to be a “sink” for excess energy storage in the form of phosphocreatine.In obes...
Women’s resistance to extractivism. A transnational embodied framework for analysis.
Mineral extraction is a foundational aspect of development, whether it is driven by fossil fuels or renewable energy sources. Extraction of minerals increasingly takes place in the...
Environmental imprinting of the Human Immune System Early in Life
Purpose and aimImmune mediated diseases originate early in life, are linked with perturbed immune-microbe interactions and are increasingly prevalent.Our hypothesis is that environ...
Optimal hydrological restoration of Swedish wetlands with deep learning and hydrogeodesy
Agricultural expansion, forestry, hydropower and road infrastructure have heavily altered the hydrological regimes of Swedish wetlands. As a result, there is a growing interest in...
The enteric nervous system connectome in health and disease
The enteric nervous system (ENS) provides the gut autonomous control of its physiology.An even broader significance of the ENS is apparent from its recently demonstrated communicat...
Strengthening resilience to climate change by improving mental health: Evidence from a randomized intervention in southwestern Uganda
People coping with extreme forms of adversity, such as armed conflict and displacement, often live in regions that depend on rainfall for agriculture and drinking water and are thu...