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15,626 grants found
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Molecular Profiling and Novel Treatment Strategies of Vascular Ageing in Chronic Kidney Disease
Cardiovascular disease due to early vascular ageing (EVA) is the leading global cause of premature death. We find a major discrepancy between chronological and biological vascular...
Shedding light on internal damage: fibre optic-driven condition assessment of corroded concrete structures
Ensuring the integrity and serviceability of our transport infrastructure is vital for the development and welfare of society.Consequently, guaranteeing the serviceability of our i...
Climate policy as a social question: Can social policies reduce opposition to carbon taxes?
Climate change is a global crisis that poses an immense challenge for both policy-makers and citizens in all countries.The determination to adopt an ambitious climate mitigation st...
Fidelity of DNA replication – cancer associated substitutions in DNA polymerase epsilon
Mutations in the proofreading domain of DNA Polymerase epsilon (builds half the human genome) have recently been defined as drivers in tumorigenesis. Here we ask whether mutations...
Science meet empiric equine orthopedics – employing objective movement analysis and computer vision for unscrambling fundamental diagnostic shortcomings.
Lameness is the most common health issue for horses today and unfortunately equine orthopaedics is a discipline with rather low scientific standard resulting in a widespread and in...
Toward sustainable textiles: Bio-based thermoplastic fibers with chemically recyclable acetal structures
This project aims to develop bio-based thermoplastic poly(acetal-urethane) fibers with sufficient mechanical properties, proper chemical recyclability and low environmental impact...
Life-course study on cardiovascular diseases: interaction between birth markers and behavioral health patterns
The risk of cardiovascular diseases (CVDs) starts in early life and accumulates across life course. So far, early-life factors and growth have not been considered in clinical manag...
When touch is painful: neural coding for affective touch
Mechanical allodynia, when a gentle touch to the skin is painful, is a clinical condition often resulting from nerve damage that has a major impact on quality of life.Crucial quest...
Local governance, professionalism and court defiance in Swedish elderly care
Swedish eldercare is based on the principle of individualized and need-based care.The law regulating eldercare, the Social Services Act, is therefore a framework law, which gives l...
Assessing ADHD in children: A randomized controlled trial to estimate reliability, validity, and cost-effectiveness of a brief versus a comprehensive assessment protocol
ADHD is one of the most prevalent psychiatric conditions, consuming a large proportion of resources in psychiatric care, often accompanied by long waiting lists to receive proper a...
EXPLORING THE ROLE OF MELATONIN IN ISLET CELLS AND TYPE 2 DIABETES
Failure of pancreatic β-cells to release adequate amounts of insulin is the main culprit in type 2 diabetes (T2D). Efforts from us highlight melatonin, the circadian rhythm hormone...
Chromosome missegregation - eroding female fertility
Human female germ cells are highly sensitive to aneuploidy, a genetic condition that arises as a consequence of chromosome missegregation events.Approximately 40% of age-dependent...
The fungal pathogen Lecanosticta acicola: A new threat to the native Scots pine in Sweden
In early 2019, it was reported the discovery of a new pathogen (Lecanosticta acicola) in on pine in southern Sweden.Huge media attention followed for what is now perceived to be a...
The protein shift - A risk for women and children?
The Swedish government has adopted a national food strategy that supports reduced meat consumption and the transition to more sustainable protein sources. The effects of such a shi...
Involuntarily Celibate Men: Gender and Vulnerability in Times of Precarious Love
The aim of this 3-year project is to investigate how various groups of heterosexual men conceptualize and deal with experiences of involuntary celibacy, and what role conceptions o...
Increasing access to evidence-based psychological treatments for adolescent depression with technological solutions
Cognitive Behavioral Therapy (CBT) is an effective treatment for mild to moderate major depressive disorder (MDD).Yet, the majority of affected adolescents do not get access to CBT...
Understanding transmission pathways of SARS-CoV-2 to build safer indoor environments
Medium-range transport of SARS-CoV-2 by small aerosol particles is a potentially important, yet poorly understood transmission pathway of the virus.In closed indoor environments, t...
Cell-Matrix Interactions in Cancer
The overall objective is to define previously unknown and opposing roles of tissue stiffening in cancer development.Tissue stiffening occurring in most cancers is sensed by cells t...
Attitudes towards using biotechnology as a tool for species restoration
Ongoing biological research will, in all likelihood, soon make it possible to breed individuals from endangered, and even extinct, species and eventually re-introduce them in their...
Translational Control of Tumor-Associated Macrophage Immunosuppressive and Pro-metastatic Functions
Purpose and Aims Tumor-Associated Macrophages (TAMs) associate with tumor progression and poor survival.TAMs exhibit states spanning from anti-tumor/immunostimulating to pro-tumor/...