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44,293 grants found
Showing 221 – 240 of 44,293 grants
EARTHCODES: developing a novel open-source computing approach to evaluate the multi-process genesis of the sub-ridge mantle from multi-isotope data
The global radiogenic isotope dataset of mantle-derived mid-oceanic ridge basalts (MORB) shows large-scale variations, providing an invaluable record of the thermochemical history...
Targeting RBC-neutrophil interactions for the treatment of sepsis associated kidney injury.
Context Sepsis is a common and life-threatening response to infection which frequently leads to multiple organ failure. The kidney is particularly vulnerable, however the mechanism...
Towards 10-minute Magnetic Resonance Scanning in Children - Developing Accelerated Imaging Using Machine Learning
Conventional Magnetic Resonance Imaging (MRI) is very time consuming (taking over 1hour/scan) and requires patients to remain still and perform multiple breath-holds. This is parti...
Ulster University and GLeonard Limited KTP24_25R1
To develop a (semi) autonomous robotic system for use in a range of refractory and related industries, to decrease demolition time and also significantly reduce the health and safe...
Ulster University and Allsop Limited KTP24_25R1
To develop and launch to market 'DIVERSE', an innovative multilingual notetaking application tailored for HR meetings, ensuring inclusive communication and efficient reco...
North West Regional College and Hawthorn Heights Limited KTP 24_25 R1
Hawthorn Heights would like to develop become leaders in the UK and Ireland for inclusive play park (IPP) design, manufacture and installation, enabling children of all abilities t...
Harnessing Positive Deviance to Address Health Inequalities: A Community-Based Approach in Underserved Communities to Promote Equity in Non-Communicable Diseases
African and Caribbean communities in the UK often live in deprived socioeconomic conditions and have higher rates of obesity and non-communicable diseases such as diabetes and card...
Revealing and Exploiting Moiré Interface Dynamics via Optical Spectroscopy
Understanding the arrangement of atoms when individual atomic sheets are combined is crucial for unlocking their unique optical and electronic properties.Recent advances in 2D tran...
THE ROLE OF SYNAPSE POLARITY ON THE FORMATION AND PLASTICITY OF INHIBITORY CONNECTIONS
In adults, GABA acts as the primary inhibitory neurotransmitter, but during early development, GABAergic synaptic transmission has depolarising effects and can influence various de...
The role of SYNGAP1 isoforms in brain development
Synaptic Ras GTPase activating protein (SynGAP) is crucial for neuronal communication and is highly concentrated in excitatory synapses.Mutations in the SYNGAP1 gene cause SYNGAP1-...
PHOS-SVD: PHOSpholipids in Cerebral Small Vessel Disease
Cerebral small vessel disease (SVD) is the leading cause of vascular dementia, plays a significant role in Alzheimer's disease and increases stroke risk, highlighting its crit...
Lithium point-of-care testing to improve adherence to monitoring guidelines and quality of maintenance therapy for bipolar disorder: a randomised feasibility trial.
Lithium is the first-line treatment for bipolar disorder.Due to its narrow therapeutic window and risk of toxicity, people taking lithium require regular blood testing to monitor l...
Optimising transient ischaemic attack (TIA) pathways to reduce ethnicity-based inequalities
AimTo reduce ethnicity-based inequities in access to and delivery of TIA pathways to improve stroke outcomes for people from ethnic minority groups. Research Questions (RQ) 1 Does...
Long-term antidepressant use and discontinuation in areas of high multiple deprivation
Background: The volume of antidepressant prescriptions has been increasing, with evidence that 30-50% of users may not need them. Antidepressants can be associated with adverse eff...
A randomised controlled feasibility study investigating surface neuromuscular STIMulation as an exercise therapy versus usual care in people with multiple sclerosis to help improve lower limb strength, walking and fatigue (STIM-MS)
Research question Is it feasible to conduct a randomised controlled trial with parallel economic evaluation of the effectiveness and cost effectiveness of surface neuromuscular ele...
RAtionalising Psychotropic medications for adults with Intellectual Disabilities: sCOPing (RAPID-COP).
Research questions Are there an adequate number of prescribers in the UK who see the need for a “StruCtured prOgramme of Psychotropic rationalisation in pEople with intel...
Desmopressin for reversal of Antiplatelet drugs in Stroke due to intracerebral Haemorrhage 2 (DASH-2)
Background Intracerebral haemorrhage causes 3.4 million deaths per year. Outcome is worse in patients with intracerebral haemorrhage who are taking antiplatelets.The number of peop...
Privacy-Preserving Human MObility Trajectory Data GeneratOr
People travel and leave their location history as mobility trajectory data.This data is invaluable for a wide range of location-based services, including city planning, traffic con...
Wafer scale dielectrics on two-dimensional semiconductors for high-performance field effect transistors
The current semiconductor market – dominated by field effect transistors (FETs) is valued at $607.40 billion per year (projected to reach $980.80 billion by 2029). A significant po...
Superconducting Parametric Amplifier Receiver Technology for Astronomy and Fundamental Physics Experiments
The emerging technology of superconducting parametric amplifiers (SPAs) can achieve quantum-limited sensitivity over a broad bandwidth by utilizing the wave-mixing mechanism in a n...