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44,293 grants found
Showing 261 – 280 of 44,293 grants
Evaluating Env-specific antibodies for the diagnosis and treatment of complex human diseases
Human endogenous retroviruses (HERV) are highly repetitive sequences that are remnants of viral infections successfully integrated in the genome.Aberrant expression of HERV envelop...
Mechanisms of Water Sensing in Plant Roots
Water stress is a pressing global challenge for agriculture, particularly given hostile climate change. Plants have the remarkable ability to shape their roots to forage for water....
Political Process Preferences in Europe: Rethinking Conceptual, Ontological and Methodological Foundations
To understand the levels of dissatisfaction with democratic performance in Europe, as well as the most effective reforms for addressing it, requires an understanding of citizens’ p...
Revealing liver micrometastases in vivo using ultra-high definition MRI
Over 90% of cancer-related deaths are caused by metastases.A major obstacle for accurate patient stratification, development of new treatments against metastases and thorough biolo...
Medicines prescribed in pregnancy: assessing safety for mother and baby using routine NHS data
Research question Which medications prescribed in primary care are the most likely to be harmful to mother or baby when prescribed in pregnancy? Background Medication use in pregna...
Sleep Apnoea Symptoms And Prevalence In People Attending Memory Services
Research Question We want to improve quality of life and brain health by treating sleep apnoea in people with who present to memory clinics. Here we ask how best to deliver a futur...
The 4th Multicentre Intrapleural Sepsis Trial (MIST4) - a definitive randomised clinical effectiveness study comparing initial video assisted thoracic surgery and intrapleural enzyme therapy in adult patients with pleural infection.
Research questionIs Video Assisted Thoracoscopic Surgery (VATS) superior to Intrapleural Enzyme Therapy (IET) in the initial treatment of adult patients with pleural infection? Bac...
The evolution and development of mechanochemical patterning systems mediating integumentary appendage emergence
Biological patterning involves the spatial organisation of cells and tissues from homogenous states into complex forms, and therefore underlies the development of all living system...
Electro-Thermal Physics in NexGen Fast Charging Batteries: Re-evaluate Heat Evolution and Thermally Safe Operation temperature
Fast charging for lithium batteries still faces challenging issues like fast heat generation, uneven electrochemical stress and side reactions like dendrites growth and solid-elect...
Artificial molecular machines in membranes: transmembrane relays for ion transport, catalysis and cargo pumping
This program will develop artificial molecular machines confined within lipid bilayer membranes, to control transmembrane transport and catalysis in cellular systems. Molecular mac...
Promiscuous Print: Legal Deposit Libraries, Rejected Texts, and New Methods for Negative Bibliography
PROMPRINT will uncover and analyze the rejects of legal deposit: the printed texts excluded from the ostensibly universal archive promised by copyright libraries. Legal deposit wor...
The Shelterin-chromatin interplay in telomere homeostasis and genome stability
The linear ends of eukaryotic chromosomes are formed by telomeres, nucleoprotein structures containing double-stranded TTAGGG repeats, ending in a single-stranded DNA 3-overhang. I...
EPSRC Centre for Doctoral Training in Applied Quantum Technologies
Quantum Technology is based on quantum phenomena that govern physics on an atomic scale, enabling key breakthroughs that enhance the performance of classical devices and allow for...
CBET-EPSRC - Nano-Embossed Microwave Photonic Sensors
This project seeks to develop a high-sensitivity, low-cost sensor platform with a wide range of uses. To bring focus to the work, we will target for point-of-care bio-sensing, and...
The Secret Metronome of Solar and Stellar Flares
The physics of flares, ferocious explosions on the Sun and other magnetically active stars, remains an enigmatic question in plasma astrophysics. One of the intrinsic features of f...
Advancing biomedical data science careers
Data and data science are transforming the world and data science expertise is in extremely high demand. Particularly within biomedical research, there is an urgent need for a shar...
The role of oculoproprioception in the neural control of ocular alignment: Understanding disease mechanisms in strabismus
Strabismus (squint or crossed eyes) is one of the most common and debilitating eye disorders in childhood. Individuals with this condition cannot align the two eyes to look at the...
Simulating the beginnings of planet formation
Protostars are born with dusty gas discs, as part of the star-forming process. Planets form within these protoplanetary discs through the gradual growth of solid dust particles int...
PINN-PORT: Automated Physics-Informed Neural Network Modeling and Application Software for Tsunami Risk Assessment in Ports: Application to Indonesia
Project PINN-PORT aims to develop an automated GIS framework and two application software for assessing tsunami hazards andtheir impact on industrial infrastructures in ports. The...
Mapping tumour molecular mechanisms associated with common exposures: a new approach to identifying targets to prevent and treat cancer
Every year, over 360,000 people in the UK are diagnosed with cancer and around 160,000 die as a result of the disease. Cancer costs the NHS over £5 billion annually, whil...