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44,293 grants found
Showing 40,961 – 40,980 of 44,293 grants
Acute multimorbid hospital presentations and breathlessness in sub-Saharan Africa
With increasing life expectancy, the number of patients with more than one chronic condition (multimorbidity) is increasing globally. Under-diagnosis and under-treatment of multimo...
Open Research Central
The open access movement has demonstrated that “openness” is a benefit to the creation, dissemination, and reuse of knowledge.Through a variety of policies and initiatives, there i...
Biomedical Vacation Scholarship Programme - University of Dundee
This award is for 6 students per year for 5-years.It includes ?a salary at the national living wage plus holiday pay and national insurance or equivalent,?as well as?funds to cover...
Stewarding the Digital Commons
Reimagining: On completing the activities, I will have collaboratively re- imagined rhythms, pace, practices, planning and policies of an inclusive, interdisciplinary research cycl...
Care, infrastructures and antiblackness: the making of biomedicine in a Sierra Leonean hospital
The research project offers an in-depth analysis of the conflation between biomedical practice, care and antiblackness in the colonial wake.Using historical, geographic and ethnogr...
A Biorepository for Research in Child Health
We propose to create an African biorepository and linked comprehensive database to support cross-disciplinary research that advances child health.The biorepository will consolidate...
Protein phosphorylation dynamics: investigating a new dimension of regulatory control during mitosis
Protein phosphorylation regulates protein function in a switch-like manner.Although each phosphorylation site only exists in two states (on/off), the frequency of switching between...
Mitochondrial dynamics in CNS health and disease
The tight regulation of mitochondrial transport and anchoring in brain cells is essential for providing ATP at the correct spatial location to power neural function and computation...
Advancing product development and use of monoclonal antibodies for infectious disease in low and middle income countries (LMICs)
Identification and development of mechanisms to accelerate development of and increase access to infectious disease mAbs for LMICs in particular to address the production costs of...
Enabling ISARIC Clinical Characterisation Protocol (CCP) roll out in LMICs
By bringing GOARN Research and ISARIC partners together in the LMIC setting during COVID-19 we hope to strengthen the clinical, social science and operational research response.Aim...
Interplay between neural stem cell states and the cell cycle in the Drosophila brain
cell fate
Wellbeing Impact Study of HS2 (WISH2)
RESEARCH QUESTION:Do individuals and communities exposed to the High-Speed Rail 2 development (HS2) a large national transport infrastructure project experience positive or negativ...
Iron deficiency and elective cardiac surgery: Prevalence, diagnosis and bone marrow iron repletion following intravenous iron
Iron is essential for oxygen-transport and many other cell functions.When done, blood tests suggest that up to 50% of patients scheduled for cardiac surgery, with or without anaemi...
Cellular zinc is at the heart of sarcoplasmic reticulum calcium leak in cardiac muscle
In the failing heart, calcium cycling is profoundly altered leading to leak of calcium from the sarcoplasmic reticulum (SR). This results in impaired contraction of cardiac tissue...
Defining nanoscopic structure-function relationship of α-Synuclein aggregates in neurodegenerative disorders
This study hypothesises that the clinical and pathologic features of each synucleinopathy disorder is encoded by a distinct conformation of the aggregated α-synuclein (αSyn).Synucl...
Research Investigating the molecular basis of cataract formation using time-resolved crystallography
This project will involve the application of state-of-the-art X-ray crystallographic techniques, developed by the PI, to investigate the molecular processes that lead to the format...
Investigating the role of WNK1 in T cell killing
Cytotoxic CD8 T Lymphocytes (CTL) are a critical component of the adaptive immune system and are responsible for clearing virus infected cells and cancer cells by secreting a deadl...
Developing statistical methods to improve the diagnosis and care of hospitalised patients with COVID-19
This research will develop innovative, and generalisable, statistical methods to assess the relationship between, and utility of, combinations of diagnostic tests for healthcare de...
The unexpected consequences of antifungals on innate immune interactions
Drug-resistant fungi are an emerging clinical problem whose interactions with the immune system are poorly understood.Candida glabrata is a facultative intracellular emerging funga...
Roles of Cryptococcus cell wall dynamics during infection and antifungal drug resistance
This project aims to understand how antifungal drugs affect the Cryptococcus neoformans cell wall composition during infection.Fungal meningitis caused by Cryptococcus neoformans i...