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44,293 grants found
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Reversible modification of methionine as a mechanism to regualte protein function in the mitochondrion and secretory pathway
The function of cells and tissues is often regulated by proteins that can be switched on or off by their reversible modification. These cellular function include critical processes...
Dinitrogen Activation Using Heterobimetallic Complexes Supported by an Extended Cryptand Ligand
Fertilisers. Detergents. Nylons.All of these products are derived from ammonia, which is produced on a megaton scale every year by the Haber-Bosch process. This is one of the world...
Porous 3D Silica Nanoparticle Assemblies as Post-surgical Drug Delivery Implants to Reduce Glioblastoma Recurrence
Glioblastoma (GBM) is the most aggressive and common form of primary brain tumour in adults. GBM patients have an extremely poor median survival of < 15 months even with tre...
DINOTROPHY: Deuterium in Organic Biomarkers: A new tool to investigate the role of Marine Mixotrophy in the Global Carbon Cycle
Abstracts are not currently available in GtR for all funded research.This is normally because the abstract was not required at the time of proposal submission, but may be because i...
Sub-clonal RNASH2B/RB1 loss, luminal-to-basal transformation, and novel therapeutic vulnerabilities in metastatic prostate cancer
Advanced prostate cancer is characterised by the emergence of resistance to hormone therapy, and is invariably fatal. The biological mechanisms underlying the evolution to an aggre...
Directing luteinising hormone receptor activity in vivo: A convergent approach to study GPCR molecular complexes
Developments in our scientific understanding of biological systems highlight the complexity and interconnected nature of such systems. When integration of biological systems fails,...
Spoiler Aerodynamics and Aeroacoustics
A PhD studentship is now available in the area of aircraft aerodynamics and aeroacoustics noise. The studentship provides a unique opportunity to work on a relevant engineering pro...
Voicing loss: Meanings and implications of participation by bereaved people in inquests
Context of the researchCoroners are independent judicial office holders appointed by the local authority. Over 40% of registered deaths in England and Wales are typically reported...
Data CAMPP (Innovative Training in Data Capture, Analysis and Management for Plant Phenotyping)
Artificial Intelligence (AI) is revolutionising agriculture and agronomy. As an example, John Deere is a near 200-year-old agriculture company which has recently transformed its bu...
Anti-infective discovery from competitive ecosystems
One of the biggest threats to global health and food security of our time is antibiotic resistance (AMR) causing existing antibiotics to become ineffective as a treatment for human...
MRC Transition Support Award CSF Tomoki Arichi
The goal of the research is to understand how injury to the brain during the crucial stages of early life in the womb and around the time of birth can lead to life-long difficultie...
Ecological drivers of the evolution of symbiosis
Beneficial symbioses are widespread in nature and underpin the function of both natural and manmade ecosystems. Moreover, by providing the interacting species with new ecological f...
Discovery of a symbiotic signalling mechanism from maize.
Symbioses are fundamental to life on the Earth. One such example, known as arbuscular mycorrhizal (AM) symbiosis, evolved between fungi and plants to facilitate mineral uptake from...
Contribution of somatosensory input to mechanisms of movement suppression during action observation
Execution of everyday movements as for example grasping of an object appears and feels effortless but requires a sophisticated mechanical machinery of muscles and joints and a comp...
VIRTACs - Protein Degradation as an Anti-Viral Strategy
As highlighted by the current Covid-19 pandemic, viruses are a constant threat to human health and prosperity.Viral infections kill millions of people every year and population gro...
Children and young people's telephone use and telephone cultures in Britain c. 1984-1999
The shift in young people's use of telephones from one-to-one voice communication to written and visual communication through texting and engagement with social media represen...
Under the skin of polishing - from nano to macro
Abstracts are not currently available in GtR for all funded research.This is normally because the abstract was not required at the time of proposal submission, but may be because i...
Low Energy Casting: : Novel induction technologies for energy efficient rapid melting
This project aims to develop new technologies to significantly improve the energy efficiency of metal casting processes for the production of quality castings with high structural...
Low Energy Casting: : Novel induction technologies for energy efficient rapid melting
This project aims to develop new technologies to significantly improve the energy efficiency of metal casting processes for the production of quality castings with high structural...
Limiting virus transmission during a Sporting Mega Event: COVID-19 and UEFA EURO 2020
The EURO 2020 football tournament, scheduled to take place across various European cities in June and July 2021, will be the first Sporting Mega Event (SME) to take place since the...