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44,293 grants found
Showing 41,301 – 41,320 of 44,293 grants
Strengthening the climate and health capacity of AfGH and SfGH
Action for Global Health (AfGH) and Students for Global Health (SfGH) in partnership aim to increase our respective health networks' (reaching more than 50 organisations), and...
Development of novel computational approaches for human cardiac mapping data - Improving understanding and treatment of atrial fibrillation
Cardiac arrhythmias are a common pathway for multiple cardiovascular diseases, the leading cause of death in the world.Ablation of cardiac arrhythmias is a recommended and common t...
Exploring the role of glypicans in modulating morphogen signalling and stem cell dynamics
Wnt and Hedgehog signalling regulate intestinal stem cell dynamics to ensure intestinal renewal, function and integrity is maintained.The activation of these two pathways involves...
Factors of biological ageing: does it all go together when it goes?
Ageing-related cognitive decline carries a huge personal, societal, and financial cost. Understanding its underlying mechanisms with a view to ameliorating age-related cognitive de...
Molecular regulators of the alarmin IL-33 in health and disease
IL-33 is a critical cytokine in allergy, obesity, helminth infection, sepsis, and respiratory viral infection.Blockade of IL-33 (or its receptor, ST2) is currently being trialled i...
Understanding Chemotaxis Towards Self-Generated Gradients Using Computational Models, Model Organisms and T cells
Cell migration is essential to processes throughout biology, especially embryonic development and immune function. Migration must be steered to be physiologically effective.Steerin...
Assessing the impact of a new class of insecticide treated net (Interceptor G2) on malaria vectors population dynamics, ecology and behaviours in the Cascades Region of Burkina Faso.
Long-Lasting Insecticide-Treated Nets (ITNs) are the most successful method for malaria vector control in Africa.Growing evidence indicates changes in mosquito vector biting and re...
University of Cambridge Translational Partnership Award
We aim to encourage and support scientists to realise the translational potential of their basic research.By the creation of a virtual Therapeutic Hub, which provides an integrated...
Tranexamic acid for hyper acute spontaneous intracerebral haemorrhage TICH-3
Research question: Does tranexamic acid (TXA) improve outcomes when given within 4.5 hours after intracerebral haemorrhage (ICH)?Background: ICH can be devastating with high early...
Developing commercialisation potential of our patented point-of-care neuropathy assessment device
Peripheral neuropathy is an increasingly common condition affecting 2.3 million people in the UK (4.5% of the population), and can lead to loss of sensation in fingers and toes. It...
The Metoclopramide for Avoiding Pneumonia after Stroke (MAPS-2) Trial: a single-blind, randomized controlled trial of metoclopramide for the prevention of pneumonia in patients with dysphagia after an acute stroke
BACKGROUND: Stroke is the most common cause of death worldwide and the foremost cause of complex disability in the UK. Pneumonia causes more deaths after stroke than the neurologic...
Olanzapine for young PEople with aNorexia nervosa: An open-label feasibility study to test recruitment, treatment acceptance, adherence, safety, outcome measures and patients' experience to prepare for a randomised placebo-controlled trial (OPEN)
Research Question: For young people with anorexia nervosa (AN), is it feasible to conduct a trial to examine the benefits and harms of prescribing olanzapine to those who have not...
A multicentre randomised controlled trial (RCT) of a self-help cognitive behavioural therapy (CBT) intervention to reduce the impact of hot flush and night sweat (HFNS) symptoms in men with prostate cancer undergoing androgen deprivation therapy (ADT): MANaging symptoms during prostate CANcer treatment (MANCAN2)
Research question: Can a self-help cognitive behavioural therapy intervention, delivered through the existing prostate cancer nurse specialist (CNS) team, reduce the impact of hot...
Evaluation of the health impacts of Universal Credit: a mixed methods study
Universal Credit (UC) combines six existing benefits and tax credits (known as legacy benefits) for working age people and their children into a single monthly payment. UC is desig...
i-Minds: A digital intervention to improve mental health and interpersonal resilience for young people who have experienced online sexual abuse - a non-randomised feasibility study with a mixed-methods design
There is no evidence-based support offered to young people who have experienced online sexual abuse (YP-OSA). NICE (2017) has recognised as a research priority the identification o...
CICADA-ME: Coronavirus Intersectionalities: Chronic Conditions and Disabilities And Migrants and other Ethnic minorities
Two groups that experience similar societal inequities (expanded by the COVID-19 pandemic), including in social and health care, are people with chronic conditions/disabilities (Pw...
Unlocking data to inform public health policy and practice: University of Sheffield
BackgroundRoutinely collected data is key to ensuring effective and responsive decision-making in Local Authorities’ (LAs’) commissioning of social care and some public health serv...
Reducing psychosis risk by targeting trauma (RESTART)
Trauma (e.g. childhood maltreatment) is a major risk factor for psychosis; epidemiological data suggests that targeting trauma could reduce psychosis incidence by 33%.We can now id...
Evaluating ICON
Research questions In infants, has implementation of the ICON programme, compared to standard newborn advice, resulted in a reduction in abusive head trauma?Amongst families and he...
The experience of people with dementia and cognitive impairment in relation to the COVID-19 pandemic: a quantitative analysis of the English Longitudinal Study of Ageing (ELSA)
This research focuses on the experience of people with dementia and cognitive impairment during the COVID-19 pandemic, and aims at quantifying the short, medium and long-term impac...