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44,293 grants found
Showing 41,621 – 41,640 of 44,293 grants
Advancing Life Sciences with Diamond-II
Diamond Light Source is an essential UK resource enabling both academic and industrial research experiments in areas as diverse as aircraft engineering, surface science, battery re...
Understanding and enhancing medicines management resilience in home-dwelling older people living with frailty.
Background: It is an NHS priority to support people to age well.For people living with frailty, the focus of support where possible should be provide tools to self-manage condition...
Spinal Medial Branch Nerve Root Block Intervention compared to Standard Care-Vertebroplasty for the Treatment of Painful Osteoporotic Vertebral Fractures in Hospitalised Older Patients: A Feasibility Study.
Research question Is a spinal medial branch nerve root block 'as clinically effective' and 'cost-effective' as routine spinal key-hole surgery, for the treatmen...
5/7 Psychiatric Genomics Consortium: Advancing Discovery and Impact
Project Summary Now in its 13th year, the Psychiatric Genomics Consortium is perhaps the most innovative and productive experiment in the history of psychiatry.The PGC unified the...
5/7 Psychiatric Genomics Consortium: Advancing Discovery and Impact
Project Summary Now in its 13th year, the Psychiatric Genomics Consortium is perhaps the most innovative and productive experiment in the history of psychiatry. The PGC unified the...
5/7 Psychiatric Genomics Consortium: Advancing Discovery and Impact
Project Summary Now in its 13th year, the Psychiatric Genomics Consortium is perhaps the most innovative and productive experiment in the history of psychiatry. The PGC unified the...
The molecular basis and evolution of host-parasite interactions in African trypanosomes
African trypanosomes are single-celled parasites that live in the bloodstream of mammals in sub-Saharan Africa and are passed between mammals though the bite of the tsetse fly. Sev...
Resurrecting ancestral sugars: a molecular archaeology approach to immunotherapy
In the last decade the precision treatment of cancer has been revolutionised.Firstly by targeted delivery of potent small molecule drugs as antibody conjugates, and subsequently by...
A combined experimental and numerical investigation of premixed flame-wall interaction in turbulent boundary layers
Abstracts are not currently available in GtR for all funded research.This is normally because the abstract was not required at the time of proposal submission, but may be because i...
The role of impaired glucagon secretion in life-threatening hypoglycaemia of type 1 diabetes: mechanism and therapeutic potential
The pancreatic islets play a central role in the regulation of blood glucose. They do so, by secreting the two hormones insulin (glucose-lowering) and glucagon (glucose-increasing)...
Modelling of elastomer composites operating in extreme conditions
Advanced drilling involves the deployment of sophisticated technologies capable of surviving extreme conditions. All the materials and in particular the elastomer composites are pu...
Determining the role of inter-kingdom interactions in the evolution of antimicrobial resistance
Polymicrobial infections consisting of Aspergillus fumigatus and Pseudomonas aeruginosa are associated with poorer patient outcomes and are often much harder to treat.There are a v...
Targeted Protein Degradation using Small Molecules
The existing paradigm for small molecule drug therapy involves interactions of drugs with their protein targets.A necessary implication of this approach is that any individual drug...
Integrated management of cryptococcal and opportunistic infections to improve outcomes in advanced HIV disease.
Background: Cryptococcal meningitis is a brain infection caused by a fungus.Approximately 250,000 cases occur every year and despite our best current treatments between a quarter a...
The Space Around Us
Project aims:- To engage children with low science capital and help them understand and get to grips with how scientists explore space through the use of big telescopes. - To encou...
Audiovisual Space: Recontextualising Sound-Image Media
The spatial turn, which swept the wider humanities, has not significantly contributed to inform our understandings of sound and image relationships. Audiovisual media are still oft...
Manufacture of a GMP SARS-CoV-2 challenge agent
In the current COVID-19 emergency, a controlled SARS-COV-2 human infection model (CHIM) has the potential to accelerate the understanding of pathogenesis, induction of immunity and...
COVID-19: Tracking Persistent Symptoms in Scotland (TraPSS)
We know that people respond very differently if they become infected with COVID19. Some people need to be admitted to hospital, while others have no symptoms at all.After treatment...
Evaluating Emerging Models Of Community Rehabilitation For People Experiencing The Effects Of Long-COVID To Inform Responsive Service Delivery Across Scotland
Studies estimate that 10–35% of people with COVID-19 experience disabling clinical symptoms following the acute phase of their illness (long-Covid).Scottish Government figures esti...
Perspectives of older couples with a learning disability when one partner has dementia: identifying support needs of carer dyads.
Background - People with a learning disability are enjoying longer lives; a 2019 survey of 1240 people with a learning disability in Scotland identified that 2.8% were married and...