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44,293 grants found
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Improving Understanding of the Biological Basis of Tinnitus: A Multi-Omics Approach in Two Large Cohorts of Women
There is a critical need to improve understanding of the biological basis of tinnitus, unravel the diverse etiologies that underlie this heterogeneous condition, and advance develo...
Hearing Loss and Dementia: Finding the Link
Our study aims to provide a strong evidential basis to explain the link between hearing loss and dementia.We will use a gene-based discovery driven approach using genetic correlati...
Preparing to Scale Oxitec’s 2nd Generation Aedes aegypti Technology in Resource-limited, Dengue-prone Urban Settings
Our team envisions a world in which dengue and other diseases transmitted by Aedes aegypti are ultimately eliminated.We believe the path to realizing this vision will require a lar...
Long-term vascular health effects of cancer and its treatment
There is increasing concern about the long-term vascular health of the large and growing population of cancer survivors.I recently showed that survivors of most types of cancer hav...
Single-cell analysis dissects clonal specific chromatin states relevant to pathology and relapse in AML
Acute myeloid leukemia (AML) is a rapidly progressing hematopoietic malignancy, characterized by the accumulation of clonal myeloid stem or progenitor cells arrested in their abili...
Improving health systems responsiveness to neglected health needs of vulnerable groups in Ghana and Vietnam
Responsive health systems improve utilisation of services and improve health outcomes. Yet, it is a least studied health systems goal, especially in low- and middle-income countrie...
21-ICRAD Plants4NemaVax; Plant-based production of glyco-engineered nematode vaccines
Parasitic nematodes are amongst the most common pathogens in grazing ruminants worldwide. The continuous exposure to these worms has a significant impact on the health status and p...
21-ICRAD: Tackling chronic wasting disease in Europe
Chronic wasting disease (CWD) is a prion disease that affects deer, similar to BSE or "mad cow disease" of cattle.Unlike BSE, there is as yet no evidence that it...
Charged Adsorbents for Capture of Carbon Dioxide Directly from Air
We face a global climate change crisis. A wide range of greenhouse gas mitigation technologies must be deployed to limit global warming to 1.5 degrees celsius at the end of the cen...
Wrapped Rib antenna into orbit and beyond
Unlike satellite based optical Earth Observation systems that rely on reflected solar radiation or thermal radiation emitted by Earth, imaging radar instruments work independently...
21 ICRAD Future rodent management for pig and poultry health (RodentGate)
Apart from consuming and spoiling animal feed, and damaging infrastructure in and around farm buildings, rodents are a considerable threat to animal health and One Health. They can...
A Complete Understanding of Massive Galaxy Formation into the Epoch of Reionization
At the frontier of modern astronomy is the study of first galaxies, when the universe was less than 10% of its current age. It is within this era that the first atoms of 'heav...
ISO-THERM: Isotopic testing of Earth's weathering thermostat
Weathering is a chemical reaction which dissolves rocks in rainwater and over long timescales removes carbon dioxide (CO2) from the atmosphere. Both theories and experiments predic...
Skout™1.0 A new system for High Footfall Security Screening for Weapons of Mass Casualty
Urban soft targets' such as stadia and large arenas have become vulnerable to mass casualty violence as terrorists exploit the inherent vulnerabilities of large crowds. The re...
Using ex vivo organotypic cultures to investigate donor cell integration in the gut
The correct functioning of the gut depends on the movement of the gut wall along the length of the bowel. This functional movement is coordinated by nerve cells within the gut call...
Designer biology to live image purine metabolism at single-cell resolution
I recently discovered the function of a previously uncharacterised gene, FAMIN, that is linked to Crohn’s disease, leprosy and arthritis.A multifunctional purine enzyme, FAMIN is t...
Probing chromatin states with single molecule microscopy
Recent research showed that the emergence of resistance in fungi can be linked to epigenetic mutations. Those are not changes in the DNA sequence, but rather in the chromatin envir...
Improving patient outcomes in the ‘hot zone’ during major incidents: a mixed-methods medical research approach.
Background During the initial phase of terrorist events, a hot zone is created where there may be on-going terrorist activities with active threats to life. The vast majority of de...
My Planet Now
My Planet Now is a cinematic short film and feature documentary for worldwide release that seek to break new ground and provide a genuine moment of global coming together on the cl...
High performance Motion Generators
Dynisma was founded in 2017 by highly experienced F1 simulator engineer Ashley Warne who had previously led the driving simulator efforts at both McLaren and Ferrari F1 teams.Our m...