Browse All Grants
44,293 grants found
Showing 42,381 – 42,400 of 44,293 grants
Germany: Creation of new tools to study the development of the human retina in a dish
Abstracts are not currently available in GtR for all funded research.This is normally because the abstract was not required at the time of proposal submission, but may be because i...
Determining how bioactive phospholipids regulate development of abdominal aortic aneurysm and coagulation using multiomic approaches
Abdominal aortic aneurysm (AAA) is an inflammatory disease with high mortality and limited treatments, associated with dysregulated coagulation and higher bleeding risk during surg...
Next generation projections of sea level contribution and freshwater export from the Greenland Ice Sheet
Loss of ice from glaciers and ice sheets is one of the most obvious consequences of global warming. As the planet warms we can expect increased rates of ice loss, and this ice ulti...
COVID and the UK nations' fiscal frameworks: impacts, performance and lessons
The UK's devolved governments (UKDGs) are responsible for much of the COVID-19 response for 10.5 million people. But they have raised concerns that the funding frameworks in w...
In vivo characterisation of 3D intervertebral disc strains
Low back pain is the leading cause of disability worldwide and is estimated to cost the NHS £500 million annually. A link has been found between degeneration of the inter...
Application of Distributed Computing for High Fidelity AC Machine Analysis
The research investigates the opportunities presented by high performance computing (HPC), both on-premises and cloud based, when applied to electrical machine design and computati...
Multimorbidity Mechanism and Therapeutics Research Collaborative
As people live to a greater age there is an increased risk of suffering more than one health condition at a time. Known as multimorbidity this has a serious effect on the daily liv...
VIPVis: Veterinary Infection Prevention through Visualisation
Antimicrobial-resistance (AMR) is a major threat to human health. Increasing numbers of resistant infections are leading to many existing antibiotics becoming ineffective.AMR is a...
Building a temporal proteomics map of the developing Caenorhabditis elegans nervous system
The highly specialized neurons that make up the nervous system of an organism develop from a small number of precursor neural cells. This development is driven by a remodelling of...
Unravelling Mechanisms Controlling Gene Expression Noise in Saccharomyces cerevisiae during Rapid Adaptive Responses
The Nrd1-Nab3-Sen1 (NNS) complex terminates transcription of approximately 12,000 RNAs in Saccharomyces cerevisiae. During the stress response, the NNS complex changes its occupanc...
Community effects in epithelial-mesenchymal transition
At different stages in life some cells acquire the ability to wander from one site to another through a process called epithelial-mesenchymal transition (EMT).This process is essen...
Coronary microvascular actions of neuropeptide Y
ST-elevation myocardial infarction (STEMI) results in high levels of cardiac sympathetic drive which is a prognostic indicator of poor outcome.We have recently shown the sympatheti...
Mucin degradation by prevalent gastrointestinal human pathogens
The overall aim of the work is to characterise the mucin degrading systems in prevalent human pathogens through a combination of transcriptomics, structural, and biochemical charac...
The New Nuclear Imperialism: Science, Diplomacy and Power in the British Empire
Responding in 1960 to the prospect of French nuclear tests in the Algerian Sahara, the leader of postcolonial Ghana, Kwame Nkrumah, forewarned of a 'new nuclear imperialism�...
Venetoclax with a hypomethylating agent or low dose cytarabine for untreated acute myeloid leukaemia when intensive chemotherapy is unsuitable [ID1564]
To appraise the clinical and cost effectiveness of venetoclax within its marketing authorisation for untreated acute myeloid leukaemia in people for whom intensive chemotherapy is...
Project GIRONA
Project GIRONA
Understanding cities in the premodern history of Northeast Asia, c. 200-1200
Northeast Asia's history is little known and much misunderstood. In the present day this region is the contact zone between China, Mongolia, North Korea and Russia. Right now...
Ponesimod for treating relapsing multiple sclerosis (ID1393)
To appraise the clinical and cost effectiveness of ponesimod within its marketing authorisation for treating relapsing forms of multiple sclerosis.
Climates of Listening: Amplifying Pacific Experiences of Environmental Crisis
Climates of Listening: Amplifying Pacific Experiences of Environmental Crisis (CoL) is the first practice-led research project to use sound and listening as a framework for expandi...
A DYNAMIC AND FLEXIBLE MANUFACTURING PLATFORM: INTENSIFYING BIOCATALYSIS FOR FRAGRANCE AND API PRODUCTION
Chemists can make novel compounds and materials, but the tools of synthetic methodology must be continuously expanded and improved for the sustainable production of compounds and m...