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44,293 grants found
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Discovery of novel personalised therapies for genetically heterogeneous, immunotherapy resistant cancers.
Cancer is the leading cause of death in the UK, a significant and hard to tackle healthcare challenge. Whilst targeted and immune therapies are improving survival, large studies in...
Intersection and Identity: Exploring the Professional and Personal Lives of Post-War Black Nurses in Britain
In 1969, 19-year-old Neslyn Watson-Druée arrived in England from Jamaica to start her nurse training. She undertook fieldwork practice as a health visitor in Brixton, wh...
"Fungal One Health and Antimicrobial Resistance Network"
Fungal infections are a growing problem, now killing more people than tuberculosis or malaria globally. Unfortunately fungi are also becoming resistant to the main anti fungal drug...
Enabling novel trait discovery for precision breeding, starting with banana
Precision breeding or gene editing is increasingly recognised as a critical tool for improving global food security and sustainability, with over 500 precision-bred crop products i...
The Live Music Mapping Project 2.0: Automating the Mapping, Modelling and Measuring of the Impacts of Regional Live Music Sectors
To achieve these, the project will:Test and develop machine learning tools for scraping the web to produce thoroughgoing - human verified - datasets covering live music ecologies....
Zwitterionic/nano modification of natural polymer-based bioinks for 3D bioprinting of advanced functional biomaterials
3D Bioprinting has recently emerged as a novel technology for developing customised, complex 3D biological constructs with great benefits for regenerative medicine.However, a signi...
Pumping iron: exploring a novel iron transporter in the early life microbiota member Bifidobacterium
Abstracts are not currently available in GtR for all funded research.This is normally because the abstract was not required at the time of proposal submission, but may be because i...
The distributional and financial impacts of the soft drinks industry levy on childhood dental caries in England
BackgroundUntreated dental caries is the most prevalent condition worldwide, affecting 2.3 billion people across all ages (26.2%) and 250 million children under 5-years (37.6%). In...
The ASK Trial: a hybrid effectiveness-implementation trial of a patient and family outreach service to improve AccesS to living-donor Kidney transplantation
Research questionDoes a patient and family outreach service improve access to living-donor kidney transplantation and is it cost-effective? BackgroundA living-donor kidney transpla...
Unlocking excellence: examining effective community mental health care for people with intellectual disability.
BackgroundPeople with intellectual disability experience higher rates of mental illness compared to the general population but have difficulty seeking support and face barriers whe...
Impact of food environment policies and food insecurity on less healthy food consumption, obesity and health economic outcomes – a model-based appraisal
Background:Obesity and food insecurity are rising in the UK, and policy makers need to identify evidence-based strategies to reduce these. Both are strongly related to environmenta...
Understanding inequalities in cancer diagnostic outcomes for people with Learning Disabilities
BackgroundThere are around 1.5 million people with learning disabilities (PwLD) in the UK. The LeDeR programme, reporting on lives and deaths of PwLD in 2022, found cancer to be th...
The NeoBath Study: Nursing babies in Neonatal Care
Research question Does the frequency of bathing babies on a neonatal unit impact upon pathogenic skin colonisation and parent preparedness for infant discharge?Background Currently...
Measuring the experience of maternity and neonatal service users - development of a maternity Patient Reported Experience Measure (PREM)
Background: The NHS needs a new patient-reported experience measure (PREM) for maternity and neonatal services that is acceptable to as many women and birthing people as possible,...
Supporting Weight Management (SWiM): Evaluating the effectiveness, equity and cost-effectiveness of using acceptance-based guided self-help to improve long term outcomes of weight management interventions
Background Clinically meaningful weight loss can be achieved cost-effectively through behavioural, pharmacological and surgical approaches and can reduce incidence and complication...
Development of new reporting guidance for systematic reviews of health economic evaluations
Research question: This project seeks to develop a reporting guideline and checklist based on expert consensus that can improve the reporting quality of systematic reviews of healt...
Target trials for talking and digital enabled therapies to estimate their real-world effectiveness, cost-effectiveness, and inequalities in outcomes using causal inference techniques applied to NHS Talking Therapies real-world data: The Target Therapies quasi-experimental study
Research question.Among referrals to NHS Talking Therapies for anxiety and depression (TTad) services, how effective and cost-effective are different talking therapies allocated fo...
PANELS – PArticipation of under-served young people in North East London health and wellbeing Services
PANELS – PArticipation of under-served young people in North East London health and wellbeing Services
Feasibility and practicability of low-burden contactless sleep tracking devices to measure objective sleep quality in sleep interventions in patients with dementia and mild cognitive impairment (SleepXacT)
Sleep problems are common in people living with dementia (PLWD), with a suggested bidirectional relationship with neurodegeneration. Sleep is also critical for quality of life and...
Development of Maternal Alcohol Reduction Interventions (MARI)
Research question: What should maternal alcohol interventions include and how can they be delivered to maximise accessibility? Background: Nondependent hazardous maternal drinking...