Browse All Grants
44,293 grants found
Showing 1,401 – 1,420 of 44,293 grants
Innovative Financing to Support Infectious Disease Research & Development (R&D;): Mapping Models and the Ecosystem for South (SA) and Southeast Asia (SEA)
There are recurring failures across the infectious disease R&D ecosystem, specifically late-stage R&D and commercialisation. Addressing these challenges requires both incre...
Developing an optimal in vitro cellular model to study the mechanism(s) of pancreas lipotoxicity in type 2 diabetes
In addition to losing normal insulin secretory function, the pancreas in type 2 diabetes (T2D) undergoes progressive loss of its mass.Remission of T2D after weight loss decreases p...
Multi-messenger signals from Massive Black hole binary systems
The next-generation space based low-frequency (1 mHz - 0.1 Hz) gravitational wave (GW) detectors, such as LISA, will probe an array of new GW sources; in particular, the inspiral-m...
What is the feasibility and acceptability of conducting a randomised controlled trial evaluating a healthcare professional- supported, self-management intervention for fatigue in ICU survivors?
Research question What is the feasibility and acceptability of conducting a randomised controlled trial (RCT) evaluating a healthcare professional (HCP)-supported, self-management...
Hyperpolarised 129Xe Nuclear Magnetic Resonance (NMR) Spectroscopic Brain Oximetry
Reductions in brain blood flow are the earliest biomarker of cognitive decline and neurodegeneration.Brain perfusion declines during ageing (Christie 2022) yet the relationship bet...
Revolutionising relative bioavailability testing: Using AI-PAT to Eliminate Animal Models
Our goal is to replace the use of animals in drug relative bioavailability studies by integrating an in-line multifunctional probe (Process Analytical Technology, PAT) into the TIM...
Bioreactor infrastructure for organoid culture in human models of reproductive diseases
Approximately 15% of all clinically recognised pregnancies end in miscarriage, mostly before 12 weeks of gestation.Apart from physical trauma (pain, bleeding, and infection), each...
Novel Bioprinters for 3D In Vitro Models (3D-IV)
Bioprinting technologies provide for an automated way of making cell cultures and co-cultures which can be applied to the production of in vitro models of tissues and diseases.In v...
Establishing a Core Infrastructure for Enhancing Gut Health, Disease and Microbiome Research Using Advanced Non-Animal Models
Modelling the gastrointestinal tract (GIT) is essential to understanding human health and disease, as it plays critical roles in digestion, immune responses, appetite regulation, a...
DNA damage deficiency in prostate cancer: functional characterisation and treatment
Sequencing profiling studies of prostate tumours have identified common alterations in genes involved in DNA damage response. Up to 10% of patients with aggressive disease show ATM...
Determination of the nature and role of the M1 and M4-muscarinic acetylcholine receptor network in regulating neuro-physiology
This PhD programme aims to address a major barrier in the development of novel treatments for Alzheimer's disease (AD).Activators of the muscarinic family of G protein-coupled...
Enhanced carbon export driven by internal tides over the mid-Atlantic ridge (CarTRidge)
Plankton in the ocean, microscopic plants (phytoplankton) and tiny animals (zooplankton) that eat the plants, are vital to marine life and to Earth's climate. They form the ba...
Global Music Technologies: Collaboration and Cultural Exchange
The history and development of musical instruments is a rich and diverse but much overlooked part of our cultural heritage. Intrinsically linked to creative expression, musical ins...
Investigating the Regulation and Replication of R-loops at Telomeres
Eukaryotic chromosomes are capped at each end by specialised nucleoprotein structures called telomeres, which are mutated or altered in essentially all incidences of cancer.Telomer...
Characterisation of adenovirus vector vaccine particles for improved antigen delivery
Doctoral Training Partnerships: a range of postgraduate training is funded by the Research Councils.For information on current funding routes, see the common terminology at https:/...
Development Of Advanced Computational Techniques To Study Next-Gen Evtol Aircraft Configurations
A promising new solution to providing a means of zero-emission transport is the eVTOL (electric Vertical Take-Off and Landing) vehicle.These new vehicles have the ability to operat...
LMO1 intracellular antibody fragments for delivery in improved treatment of childhood neuroblastoma
The LIM-only protein LMO1 is implicated in neuroblastoma by synergising with MYCN to promote tumour development and metastasis.The proposed work will use technologies we developed...
Moustachioed Women: A digital humanities investigation into the politics of female facial hair in literature, 1835-1906.
This project examines what the literary representations of moustachioed women between 1835-1906 reveal about the history and politics of facial hair that have remained prevalent to...
Computing Lagrangian means in multi-timescale fluid flows
Time averaging is one of the most essential tools in analysing fluid flows with multiple time scales, which are ubiquitous in nature and industries. A prominent use of time averagi...
Bioharmonophores imaging
In this project, we will establish a smart diagnostic probe that utilises the well-known advantages of PSMA-PET tracers with the self-assembly properties of tripeptides that form t...