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44,293 grants found
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400 Million Years of Food Transport in Plants: unearthing the origin, diversity and genetic toolkit of vasculature
Plants transport sugars around their bodies in the specialised tissue termed the phloem. The phloem is essential for plant life and underpins the growth and survival of all economi...
Nemolizumab for treating moderate to severe atopic dermatitis in people aged 12 and over or prurigo nodularis in adults [ID6221]
Atopic dermatitis (also known as atopic eczema) is a long-term condition that affects the skin. It is characterised by a blotchy rash dry itchy and inflamed skin. The skin can also...
3DIr4E: Three-Dimensional low Ir loading anodes For proton exchange membrane water Electrolyzers
Proton exchange membrane (PEM) water electrolyzers hold great significance for renewable energy storage and conversion.However, the oxygen evolution reaction (OER) at the anode has...
The Generation Gap - understanding tissue communication during grain development
Cereal grain provides more calories to our food supply than any other source. Cereal grain is also a critical feedstock for malting and brewing. Despite this, we know little about...
Fezolinetant for treating vasomotor symptoms associated with the menopause [ID5071]
The menopause occurs when menstruation stops and the end of natural reproductive life is reached. Usually it is defined as having occurred when there has been no naturally occurrin...
ELVER-CHECK: Well-grounded Lightweight Assurance for Critical Systems Software
Computer systems have become critical to modern society, but they are pervasively subject to security flaws and attacks, with large-scale exposures of confidential data, denial-of-...
NIHR Senior Clinical and Practitioner Research Award R1
Training Award
Socio-demographic trends in the identification and management of patients with aortic stenosis- a mixed methods study to establish the current status and identify areas for improving health equity
Background Aortic Stenosis (AS) is the commonest valve lesion requiring intervention in developed countries, and its incidence is rising with an ageing population. Small studies ha...
Investigating the impact of sepsis phenotypes on antibiotic treatment in patients with severe pneumonia and sepsis
Research question: Can sepsis phenotypes help explain antibiotic blood concentration variability in critically ill patients with severe pneumonia and sepsis?Background: Pneumonia i...
Randomised controlled effectiveness trial (RCT) of isometric exercise (IE) in adults with stage 1 and 2 hypertension. (ISOFITTER)
Research question To determine whether isometric exercise plus standard care significantly reduces blood pressure in Stage 1 and 2 hypertension alongside contextual implementation...
NIHR ICA Pre-doctoral Clinical and Practitioner Academic Fellowship 2024
Training Award
The development and evaluation of two Prehab interventions for patients undergoing elective and urgent heart surgery
Research questions In people undergoing elective cardiac surgery, is prehabilitation effective and cost-effective? In people undergoing urgent cardiac surgery, is prehabilitation f...
Pre-doctoral Fellowship Round 6
Training Award
Hypotension Decision Assist: software for early detection of oncoming intra-operative hypotension
Hypotension Decision Assist: software for early detection of oncoming intra-operative hypotension
NIHR Development and Skills Enhancement Award
Training Award
Facial Asymmetry in Childhood Cancer Survivors Treated with Radiotherapy
Background Clinically significant facial asymmetry occurs in 77% of children treated with head-and-neck radiotherapy (HNRT) [6]. Facial asymmetry and related dentofacial side-effec...
Image guided laparoscopic liver resection: a feasibility randomised controlled trial
Research question : The feasibility of a randomised controlled trial comparing the SmartLiver system of image guided liver surgery versus standard care in laparoscopic liver surger...
A Phase II RCT Of OrAl Cannabinoid Versus Placebo In The Treatment Of Chemotherapy Induced Peripheral NeurOpathic PaiN (ACTION)
Research questions: What is the efficacy of a broad-spectrum cannabidiol (CBD) oral tincture containing CBD isolate and terpenes in patients with neuropathic pain due to chemothera...
Modelling the effects of integrating diabetic retinopathy services in the Malawi health system
Currently, 24 million adults have diabetes in Africa, projected to rise to 55 million by 2045. Diabetic retinopathy (DR) is the most common complication of diabetes, and one of the...
Pre-doctoral Fellowship Round 6
Training Award