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201,169 grants found
Showing 196,741 – 196,760 of 201,169 grants
IMSD at Wayne State University
The mission of Wayne State University (WSU), to create and advance knowledge, prepare a diverse student body to thrive, and positively impact local and global communities, is very...
Molecular and neural mechanisms of predator cue sensation
Understanding how animals make behavioral decisions is one of the biggest problems in neuroscience. The proposed study aims to understand molecular and neural mechanisms underlying...
Developing a Novel Decision Aid for Tracheostomy to Support Shared Decision- Making in the Intensive Care Unit
PROJECT SUMMARY/ABSTRACT This NHLBI K23 Mentored Patient-Oriented Research Career Development Award (PA-18-374) submission by Anuj B. Mehta, MD will enable him to achieve his overa...
Limbix Spark: a CBT-based mobile intervention for adolescent depression
Project Abstract Depression affects more than 3.2 million adolescents in the USA, with rising incidence and suicide rates that carry devastating personal, societal, and economic im...
Immunological characterization of rationally-designed vaccines against plague in mice and non-human primate models
ABSTRACT The increasing number of bubonic/pneumonic plague cases globally (2010-2018), including the U.S., with a ~18% case fatality rate may reflect climate changes and a rodent c...
Regulation of spore peptidoglycan modification
Dr. Gabrielle Valles recently received her Ph.D. from the University of Connecticut, where she used NMR spectroscopy and X-ray crystallography to study the structure and function o...
Portable, Patient-Administered Scalp Cooling Cap to Reduce Provider Burden, Improve Patient Access, and Improve Patient Outcomes for Chemotherapy-Induced Alopecia
PROJECT SUMMARY—Approximately two-thirds of patients undergoing cancer treatment experience hair loss from chemotherapy-induced alopecia (CIA). Patients say CIA is one of the most...
Efficient estimation of auditory sensitivity and cognitive status using spoken-digit tests.
Project Summary/Abstract. Untreated age-related hearing loss (ARHL) is the most prevalent cause of reduced quality of life for persons 55 and older in the US. There are 30+ million...
Protein Networks as Synergistic Drivers of Membrane Remodeling
SUMMARY ABSTRACT: Administrative Supplement to Promote Diversity for R35GM139531 This proposal is for an administrative supplement to R35GM139531, to promote diversity through the...
Improving sleep in gynecologic cancer survivors
PROJECT SUMMARY Sleep disturbance is one of the primary complaints of gynecologic cancer survivors, with more than 80% of survivors reporting sleep difficulties. Sleep disturbance...
The role and mechanism of necrosis in glioblastoma
Project Summary Gliomas are major primary brain tumors, of which glioblastomas (GBM) are the most common and aggressive forms. The poor outcome of traditional treatment for these t...
Mechanism Shaping the Adhesion Landscape During Spinal Cord Development
PROJECT SUMMARY An important question in developmental biology is how cell fate specification and cell movement are coordinated during tissue morphogenesis to ensure all cell types...
IMSD at Rush University
Project summary/abstract: National data on career choices of emerging scientists indicate that less than 25% pursue a traditional independent pathway in an academic environment. Th...
Molecular mechanisms of the mitochondrial permeability transition
The overarching goal of my research program is to identify and characterize molecular mechanisms responsible for stress-induced permeabilization of the mitochondrial inner membrane...
CHEMISTRY CENTER FOR COMBATING ANTIBIOTIC-RESISTANT BACTERIA (CC4CARB)
The Chemistry Center for Combating Antibiotic-Resistant Bacteria (CC4CARB) will synthesize and deliver rationally designed compound libraries to the scientific community to facilit...
RAPID ACCELERATION OF DIAGNOSTICS (RADX) TECH PROJECT #6139: REVOGENE SARS-COV-2 ASSAY
Resubmission of Application 3136. This product concept has been updated to include Flu viral targets along with SARS-CoV-2.The Rapid Acute Respiratory Panel assay will be a molecul...
THE PURPOSE OF THIS MODIFICATION IS TO DE-OBLIGATE NHLBI FUNDING FROM THE WOMEN'S HEALTH INITIATIVE (WHI) - CLINICAL COORDINATING CENTER (CCC).
The overall goal of the Women’s Health Initiative (WHI) Renewal is to continue to serve as a resource for innovative epidemiological research and to expand knowledge about the dete...
Surgical Multispecialty Access to Research in Residency Training (SMART)
SUMMARY Surgeon-scientists are an underrepresented population in academic medicine, and federally funded surgeon- scientist-led research has been in decline over the past decade. S...
Bio-tribo-corrosion resistant 3D Printed Composites for Load-bearing Implants
Among load-bearing implants, total hip arthroplasty (THA) is probably the most clinically successful intervention. CoCrMo alloy, a wear resistant material of choice, is typically u...
High-throughput computational modeling to assess the role of 3D genome folding in human congenital anomalies
PROJECT SUMMARY Congenital heart defects (CHD) occur in nearly one percent of live births each year and are the leading cause of defect-associated infant mortality. The majority of...