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201,169 grants found
Showing 197,261 – 197,280 of 201,169 grants
MCSP TORFP NO. NIH-NINDS-21-01: FLORIO (ANAGIN) - BASE EC (STROKE)
The Contractor, in performance of work under this task order shall provide a full-service facility and staff who would support a medicinal chemistry discovery program beginning at...
Mapping & quantifying lymphatic drainage of the arm's alternate pathway
Project Summary/Abstract Breast Cancer Related Lymphedema affects 1.2 million patients in the United States and has no cure. The symptoms of lymphedema include fatigue, tightness,...
Remodeled airway irritant reflexes as a cause of serious cardiovascular events
Air pollutants/irritants evoke dangerous sympathoexcitatory reflexes in individuals with cardiovascular disease (CVD) but evoke sympathoinhibitory reflexes in healthy subjects. How...
FAST-FNA immune cell profiling in HNSCC
Currently, the single best predictive biomarker of response to anti-PD1 monotherapy is PD-L1 expression as assessed by immunohistochemical staining of archived or fresh tissue. Cur...
Biocascade inlet
Project Summary Respiratory infections are the most common reason for doctor visits and the third leading cause of deaths. Viruses are the causative agents of most respiratory trac...
MCSP TORFP NO. NIH-NINDS-21-01: FLORIO (ANAGIN) - BASE EC (STROKE)
The Contractor, in performance of work under this task order shall provide a full-service facility and staff who would support a medicinal chemistry discovery program beginning at...
Mapping & quantifying lymphatic drainage of the arm's alternate pathway
Project Summary/Abstract Breast Cancer Related Lymphedema affects 1.2 million patients in the United States and has no cure. The symptoms of lymphedema include fatigue, tightness,...
FAST-FNA immune cell profiling in HNSCC
Currently, the single best predictive biomarker of response to anti-PD1 monotherapy is PD-L1 expression as assessed by immunohistochemical staining of archived or fresh tissue. Cur...
Remodeled airway irritant reflexes as a cause of serious cardiovascular events
Air pollutants/irritants evoke dangerous sympathoexcitatory reflexes in individuals with cardiovascular disease (CVD) but evoke sympathoinhibitory reflexes in healthy subjects. How...
Biocascade inlet
Project Summary Respiratory infections are the most common reason for doctor visits and the third leading cause of deaths. Viruses are the causative agents of most respiratory trac...
Schwann Cell Regulation of Hematopoiesis
Project Summary/Abstract: Physiologic blood cell production is regulated by peripheral nerve fibers that innervate the bone marrow.Aging, diabetes, neurotoxic drugs and certain mye...
Imaging sodium and lymphatics in lymphedema
The overall goal of this work is to investigate lymphatic vascular mechanisms of tissue sodium handling using novel, noninvasive imaging tools sensitive to sodium and lymphatics in...
Exploring the Limits of Ribosome Mediated Polymerizations for Expanding the Genetic Code
PROJECT SUMMARY Recombinant protein production (RPP) has become a powerful tool for producing life-saving therapeutics such as insulin, monoclonal antibodies, and other critical bi...
Core Fucosylation of N-linked Glycans as a Regulator of CD8+ T cell Activation and Function
PROJECT SUMMARY/ABSTRACT Post-translational carbohydrate modifications are important mediators of several cellular processes including protein turnover, cell adhesion, signal trans...
Solute carrier proteins in efferocytosis and inflammation
Abstract: SOLUTE CARRIER (SLC) PROTEINS IN EFFEROCYTOSIS AND INFLAMMATION: It is truly remarkable that our bodies turn over on average about one million cells every second of life....
B WELL MOM FATTY ACID PROFILE
The purpose of the Breathe ?Wellbeing, Environment, Lifestyle and Lung Function Study (B-WELL Mom Study) is to examine the role of asthma control in pregnancy outcomes.This study e...
Admin. Supp. for NCI P30 Cancer Center Grants to Facilitate the Development of Standardized Electronic Treatment Plan Builds for NCI-Supported Clinical Trials Applicable Across Clinical Research Sites
PROJECT SUMMARY Electronic health records (EHR) are used in all NCI-supported Cancer Centers.EHR data support not only the delivery of standard-of-care treatments, but also investi...
Schwann Cell Regulation of Hematopoiesis
Project Summary/Abstract: Physiologic blood cell production is regulated by peripheral nerve fibers that innervate the bone marrow. Aging, diabetes, neurotoxic drugs and certain my...
Solute carrier proteins in efferocytosis and inflammation
Abstract: SOLUTE CARRIER (SLC) PROTEINS IN EFFEROCYTOSIS AND INFLAMMATION:It is truly remarkable that our bodies turn over on average about one million cells every second of life....
Imaging sodium and lymphatics in lymphedema
The overall goal of this work is to investigate lymphatic vascular mechanisms of tissue sodium handling using novel, noninvasive imaging tools sensitive to sodium and lymphatics in...