Browse All Grants
201,169 grants found
Showing 198,061 – 198,080 of 201,169 grants
Rational translation of gold nanoparticle mediated radiosensitization tothe clinic
The use of high atomic number (Z) elements as radiosensitizers of tumors has been well documented in the literature over the last few decades.In particular, gold nanoparticles (GNP...
Inflammation, Social Networks, and Depression in Rural Uganda
PROJECT SUMMARY Major depressive disorder is one of the top 5 contributors to years lived with disability among adults in sub- Saharan Africa.Numerous studies have suggested a link...
mHealth Facilitated Intervention to Improve Medication Adherence among Persons Living with HIV
There are more than a million persons living with HIV in the United States.Despite the effectiveness of antiretroviral therapy (ART), viral suppression, particularly durable viral...
OPTION PERIOD ONE (1): DIVERSITY SUPPLEMENT FOR MORGAN JONES - JACKSON HEART STUDY (JHS) TRAINING AND EDUCATION CENTER (TEC)
The Jackson Heart Study (JHS) is a single-site prospective epidemiologic investigation of cardiovascular disease (CVD) among African-Americans from the Jackson, Mississippi metropo...
RADX-TECH - SUPPORT SERVICES NEEDED FOR WORK PACKAGE 1
We are building a small, easy-to-use point of care device to simultaneously detect both viral RNA (current infection) and IgG antibody (past infection) markers from saliva. The tes...
Inflammation, Social Networks, and Depression in Rural Uganda
PROJECT SUMMARY Major depressive disorder is one of the top 5 contributors to years lived with disability among adults in sub- Saharan Africa. Numerous studies have suggested a lin...
mHealth Facilitated Intervention to Improve Medication Adherence among Persons Living with HIV
There are more than a million persons living with HIV in the United States. Despite the effectiveness of antiretroviral therapy (ART), viral suppression, particularly durable viral...
RNA tools for probing spliceosome dynamics
Project Summary/Abstract Alternative splicing is a central mechanism to diversify genetic information on the post-transcriptional level. Advances in sequencing technologies reveale...
Altering Cardiac Cell Fate for Heart Repair
Abstract Direct cardiac reprogramming holds great promise as a novel therapy for heart failure, a common and morbid disease that is usually caused by irreversible loss of massive f...
Controllable 2- and 3D Assembly of Mechanically Robust Skin Tissue Via Long Term Expression of DNA on Cell Membranes
The proposed research plan will develop innovative bioconjugation and DNA-mediated cell assembly strategies for rapid creation of self-assembled multicellular scaffolds with progra...
Rational translation of gold nanoparticle mediated radiosensitization tothe clinic
The use of high atomic number (Z) elements as radiosensitizers of tumors has been well documented in the literature over the last few decades. In particular, gold nanoparticles (GN...
Relating Molecular Subgroups of Endometriosis-Associated Ovarian Cancers to Survival and Risk
PROJECT SUMMARY/ABSTRACT Ovarian cancer (OC) is the eleventh most common cancer and fifth deadliest among U.S. women. The low incidence, high fatality and molecularly broad range o...
RUNX:CBFb complex constrains fetal-restricted innate T cell generation from adult lymphopoietic progenitors
SummaryDuring intrauterine development the immune system generates cell subsets that will colonize mucosal barriers. This process is restricted to a fetal/neonatal window as adult...
Investigating the role of Eya3 in the regulation of innate immune signaling cascades in Triple Negative Breast Cancer
PROJECT SUMMARY/ABSTRACT: Triple Negative Breast Cancer (TNBC) is a subtype of breast cancer characterized by low or absent expression of the estrogen receptor and the HER2 growth...
An Engineered Nanocarrier Platform for Enhancing Immune Responses to Neoantigen-Targeted Cancer Vaccines
Project Summary Vaccines targeting cancer neoantigens have the potential to enhance the magnitude, function, and duration of an anti-tumor T cell response, offering a promising str...
Damage-Associated Molecular Patterns Driving Fibrosis Progression in Scleroderma
June 3 2018 ABSTRACT Synchronous fibrosis in multiple organs is the defining hallmark of systemic sclerosis (SSc), but its pathogenesis remains poorly understood, and there is an u...
Altering Cardiac Cell Fate for Heart Repair
Abstract Direct cardiac reprogramming holds great promise as a novel therapy for heart failure, a common and morbid disease that is usually caused by irreversible loss of massive f...
Relating Molecular Subgroups of Endometriosis-Associated Ovarian Cancers to Survival and Risk
PROJECT SUMMARY/ABSTRACT Ovarian cancer (OC) is the eleventh most common cancer and fifth deadliest among U.S. women. The low incidence, high fatality and molecularly broad range o...
Relating Molecular Subgroups of Endometriosis-Associated Ovarian Cancers to Survival and Risk
PROJECT SUMMARY/ABSTRACT Ovarian cancer (OC) is the eleventh most common cancer and fifth deadliest among U.S. women.The low incidence, high fatality and molecularly broad range of...
RUNX:CBFb complex constrains fetal-restricted innate T cell generation from adult lymphopoietic progenitors
Summary During intrauterine development the immune system generates cell subsets that will colonize mucosal barriers. This process is restricted to a fetal/neonatal window as adult...