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201,169 grants found
Showing 198,121 – 198,140 of 201,169 grants
CORE A - Administrative Core
PROJECT SUMMARY The Administrative Core will coordinate the administrative, fiscal, and organization aspects of our PPG program. Personnel in this Core will facilitate scientific c...
Application of mild therapeutic hypothermia for hearing conservation during cochlear implant surgeries
Project Summary More than half a million patients, including children, have benefitted from the remarkable technological breakthrough that are cochlear implants (CI).An increasing...
Neural Mechanisms of Mindfulness-Based Stress Reduction in Adults with Autism Spectrum Disorder
Project Summary/Abstract Adults with autism spectrum disorder (ASD) suffer from depression at up to four times the rate of the general population.Mindfulness-Based Stress Reduction...
Elucidating the Function of LRP1 in APOE-mediated Suppression of Melanoma Metastasis
PROJECT SUMMARY/ABSTRACT Metastatic melanoma is the cause of over 80% of skin cancer deaths.Previous work in our lab interrogating the molecular differences between highly and poor...
Utilization of Advanced Technologies for the Understanding of Human Structural Birth Defects
PROJECT SUMMARY The unifying theme of this proposal is the aim to use state-of-the-art technologies to investigate the basic biology of mammalian organ development and human struct...
Adaptation and optimization of the Friendship Bench mental health intervention for adolescent girls and young women in South African PrEP delivery settings
ABSTRACT The goal of the proposed K99/R00 award is to support Dr.Jennifer Velloza?s development into an independent HIV and mental health researcher, with a focus on improving deli...
Incorporation of multilevel ontologies of adverse events and vaccines for vaccine safety surveillance
Incorporation of multilevel ontologies of adverse events and vaccines for vaccine safety surveillance PROJECT SUMMARY Vaccines face tougher safety standards than most pharmaceutica...
Neural Mechanisms of Mindfulness-Based Stress Reduction in Adults with Autism Spectrum Disorder
Project Summary/Abstract Adults with autism spectrum disorder (ASD) suffer from depression at up to four times the rate of the general population. Mindfulness-Based Stress Reductio...
Application of mild therapeutic hypothermia for hearing conservation during cochlear implant surgeries
Project Summary More than half a million patients, including children, have benefitted from the remarkable technological breakthrough that are cochlear implants (CI). An increasing...
Incorporation of multilevel ontologies of adverse events and vaccines for vaccine safety surveillance
Incorporation of multilevel ontologies of adverse events and vaccines for vaccine safety surveillance PROJECT SUMMARY Vaccines face tougher safety standards than most pharmaceutica...
Utilization of Advanced Technologies for the Understanding of Human Structural Birth Defects
PROJECT SUMMARY The unifying theme of this proposal is the aim to use state-of-the-art technologies to investigate the basic biology of mammalian organ development and human struct...
Incorporation of multilevel ontologies of adverse events and vaccines for vaccine safety surveillance
Incorporation of multilevel ontologies of adverse events and vaccines for vaccine safety surveillance PROJECT SUMMARY Vaccines face tougher safety standards than most pharmaceutica...
Elucidating the Function of LRP1 in APOE-mediated Suppression of Melanoma Metastasis
PROJECT SUMMARY/ABSTRACT Metastatic melanoma is the cause of over 80% of skin cancer deaths. Previous work in our lab interrogating the molecular differences between highly and poo...
Adaptation and optimization of the Friendship Bench mental health intervention for adolescent girls and young women in South African PrEP delivery settings
ABSTRACT The goal of the proposed K99/R00 award is to support Dr. Jennifer Velloza’s development into an independent HIV and mental health researcher, with a focus on improving del...
Project I - Transcriptomic Analysis of Structural Birth Defects in Mouse Developmental Mutants
PROJECT SUMMARY In this project we plan to apply a powerful and scaleable technique of combinatorial indexing to characterize gene expression at the single-cell level in mice carry...
Project II - 3D Quantitative Analysis of Mouse Models of Structural Birth Defects Through Computational Anatomy
PROJECT SUMMARY E15.5 fetuses of 6 homozygous mutants from each of the 85 sci-RNA-seq lines will be acquired from Project 1 to be imaged via high-resolution microCT following estab...
Project III - Comprehensive Genomic Evaluation of Structural Birth Defects
PROJECT SUMMARY Structural birth defects (SBD) affect 3-6% of live births and are a leading cause of infant morbidity and mortality worldwide. Most SBD are isolated, occur in the f...
Elucidating the Function of LRP1 in APOE-mediated Suppression of Melanoma Metastasis
PROJECT SUMMARY/ABSTRACT Metastatic melanoma is the cause of over 80% of skin cancer deaths. Previous work in our lab interrogating the molecular differences between highly and poo...
Adaptation and optimization of the Friendship Bench mental health intervention for adolescent girls and young women in South African PrEP delivery settings
ABSTRACT The goal of the proposed K99/R00 award is to support Dr. Jennifer Velloza’s development into an independent HIV and mental health researcher, with a focus on improving del...
Furopyrimidines as novel inhibitors of henipaviruses
The emergence and reemergence of pathogenic viruses represent continuous infectious disease threats to public health.Among these, the paramyxoviruses, which include many important...