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201,169 grants found
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Positive and Negative Psychological Predictors of Long-Term Recovery after Cardiac Arrest
With advances in healthcare and effective public health campaigns, the survival rate after cardiac arrest (CA) has more than doubled during the last decade. However, as highlighted...
MIRA: The biological basis of paternal care in stickleback fish
Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. The Abstract is unchanged.Parental care is crit...
Dissecting roles of microbiome-host interactions in colorectal neoplasia etiology using multi-omics data
PROJECT SUMMARY Microbiome dysbiosis has been increasingly recognized to be associated with colorectal neoplasia, including colorectal adenoma and colorectal cancer (CRC). Disturba...
Preclinical Development of GV-MVA-VLP Vaccines Against COVID-19
PROJECT SUMMARY With unprecedented speed and scale, SARS-CoV-2 has caused a deadly global pandemic. A safe and effective vaccine to control this new pathogen is desperately needed....
Machine learning with immunogenetics for the prediction of hematopoietic cell transplant outcomes
ABSTRACT Allogeneic hematopoietic cell transplantation (HCT) is the only curative treatment for most forms of acute myelogenous leukemia (AML), but its 50% failure rate remains una...
ELECTRONIC CIGARETTE VAPING & VASCULAR SEQUELAE IN THE UTERUS DURING PREGNANCY
ELECTRONIC CIGARETTE VAPING & VASCULAR SEQUELAE IN THE UTERUS DURING PREGNANCY Despite serious pregnancy complications, 50% of women who use tobacco products will continue to d...
Positive and Negative Psychological Predictors of Long-Term Recovery after Cardiac Arrest
With advances in healthcare and effective public health campaigns, the survival rate after cardiac arrest (CA) has more than doubled during the last decade.However, as highlighted...
Bayesian Hierarchical Methods for Localized Analysis of Genic Intolerance to Variation
Project Summary: The goal of this proposed mentored research is to tie genetic variation to disease by analyzing regions that are intolerant to variation.Identifying regions that a...
MIRA: The biological basis of paternal care in stickleback fish
Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. The Abstract is unchanged.Parental care is crit...
ELECTRONIC CIGARETTE VAPING & VASCULAR SEQUELAE IN THE UTERUS DURING PREGNANCY.
ELECTRONIC CIGARETTE VAPING & VASCULAR SEQUELAE IN THE UTERUS DURING PREGNANCY Despite serious pregnancy complications, 50% of women who use tobacco products will continue to d...
Molecular mechanisms of NFIB in small cell lung cancer metastasis
PROJECT SUMMARY Most cancer patients do not die from their primary tumor but from their metastases. In spite of the morbidity and mortality associated with metastatic disease, rela...
Molecular Mechanisms of Susceptibility to Drug Use
PROJECT SUMMARY / ABSTRACT The transition from drug use to abuse and, eventually, to dependence may be mediated by biological factors that are present prior to drug use. Although c...
Thermodynamic and Allosteric Basis of Paradoxical Activation in V600E Mutant BRAF Cancers
PROJECT SUMMARY The activating V600E mutation in the protein kinase BRAF is a well-established driver of human cancer. The effectiveness of current BRAF inhibitors developed to tar...
Determining the role of LSD1 in multiple myeloma through a multi-omics approach at single cell resolution
PROJECT SUMMARY / ABSTRACT Multiple myeloma (MM) kills nearly 13,000 people annually in the United States1. MM is preceded by a less life- threating blood condition, which is simil...
Link, transport, integrate: a Bayesian data integration framework for scalable algorithmic dementia classification in population-representative studies
Project Summary Nationally representative cohorts are crucial for monitoring population trends in incidence, prevalence, and disparities in Alzheimer’s disease (AD) and Alzheimer’s...
Molecular Mechanisms of Susceptibility to Drug Use
PROJECT SUMMARY / ABSTRACT The transition from drug use to abuse and, eventually, to dependence may be mediated by biological factors that are present prior to drug use. Although c...
Molecular Mechanisms of Susceptibility to Drug Use.
PROJECT SUMMARY / ABSTRACT The transition from drug use to abuse and, eventually, to dependence may be mediated by biological factors that are present prior to drug use. Although c...
Determining the role of LSD1 in multiple myeloma through a multi-omics approach at single cell resolution
PROJECT SUMMARY / ABSTRACT Multiple myeloma (MM) kills nearly 13,000 people annually in the United States1. MM is preceded by a less life- threating blood condition, which is simil...
Molecular Mechanisms of Susceptibility to Drug Use.
PROJECT SUMMARY / ABSTRACT The transition from drug use to abuse and, eventually, to dependence may be mediated by biological factors that are present prior to drug use. Although c...
The Impact of Gut Microbiota on the Sex Difference in Bladder Cancer
Men are 3-5 times more likely than women to develop and die from bladder cancer (BCa) but the underlying mechanisms of these gender disparities in BCa are poorly understood.This is...