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201,169 grants found
Showing 198,381 – 198,400 of 201,169 grants
Community Engagement
COMMUNITY ENGAGEMENT SUMMARY NMRFAM has a long history of providing service and access to new technology to the NMR community. We continue this tradition as we move into new techno...
Designing Ligand Platforms of Titanium Imido Catalysts and Statistically Screening Alkyne Substrates for [2+2+1] Regioselective Pyrrole Synthesis
Project Summary/Abstract Substituted pyrroles are pivotal organic building blocks in pharmaceuticals, materials, and natural products, however, these scaffolds are often difficult...
Transcriptome-driven inference of adverse drug interactions
ABSTRACT Ototoxicity is a debilitating side effect of over 150 medications, many of which are prescribed as part of multi- drug regimens to treat a broad range of conditions includ...
Designing Ligand Platforms of Titanium Imido Catalysts and Statistically Screening Alkyne Substrates for [2+2+1] Regioselective Pyrrole Synthesis
Project Summary/Abstract Substituted pyrroles are pivotal organic building blocks in pharmaceuticals, materials, and natural products, however, these scaffolds are often difficult...
Transcriptome-driven inference of adverse drug interactions
ABSTRACT Ototoxicity is a debilitating side effect of over 150 medications, many of which are prescribed as part of multi- drug regimens to treat a broad range of conditions includ...
Administration and Management
ADMINISTRATION AND MANAGEMENT SUMMARY Our goal is to develop a plan for administration and management to ensure that the biotechnology research resource operates productively and e...
Expanding the Scope of NMR Sample Preparation
TR&D 1 SUMMARY This technology research and development project targets two major challenges for solid-state NMR and structural biology. First, sample handling represents a maj...
Technologies for Solid-State NMR Data Collection
TR&D 2 SUMMARY The overall performance of the NMR spectrometer impacts every research sample and outcome. Often for complex multidimensional magic-angle spinning solid-state NM...
Driving Biomedical Projects
DRIVING BIOMEDICAL PROJECTS SUMMARY Development of new technology is driven by the desire to perform experiments for which the tools do not yet exist. Our driving biomedical projec...
Community Engagement
COMMUNITY ENGAGEMENT SUMMARY NMRFAM has a long history of providing service and access to new technology to the NMR community. We continue this tradition as we move into new techno...
Exploration of a Novel Therapeutic for Alzheimer's Disease and Related Disorders
“Exploration of a Novel Therapeutic for Alzheimer’s Disease and Related Disorders” Project Summary / Abstract Neurodegenerative disorders are responsible for progressive loss of sy...
Integrated NMR for Complex Systems
TR&D 3 SUMMARY Assigning each resonance in an NMR spectrum to individual atoms in a molecule is essential to almost every NMR project. Automated programs are successful for ass...
Driving Biomedical Projects
DRIVING BIOMEDICAL PROJECTS SUMMARY Development of new technology is driven by the desire to perform experiments for which the tools do not yet exist. Our driving biomedical projec...
Community Engagement
COMMUNITY ENGAGEMENT SUMMARY NMRFAM has a long history of providing service and access to new technology to the NMR community. We continue this tradition as we move into new techno...
NMR Technologies for Integrating Structure, Function and Disease
INTRODUCTION TO REVISED APPLICATION The A0 grant was submitted in May 2019, before Prof. Alexander Barnes moved to ETH-Zurich and before Prof. Chad Rienstra was recruited to UW-Mad...
Transcriptome-driven inference of adverse drug interactions
ABSTRACT Ototoxicity is a debilitating side effect of over 150 medications, many of which are prescribed as part of multi- drug regimens to treat a broad range of conditions includ...
NMR Technologies for Integrating Structure, Function and Disease
INTRODUCTION TO REVISED APPLICATION The A0 grant was submitted in May 2019, before Prof. Alexander Barnes moved to ETH-Zurich and before Prof. Chad Rienstra was recruited to UW-Mad...
Administration and Management
ADMINISTRATION AND MANAGEMENT SUMMARY Our goal is to develop a plan for administration and management to ensure that the biotechnology research resource operates productively and e...
Expanding the Scope of NMR Sample Preparation
TR&D 1 SUMMARY This technology research and development project targets two major challenges for solid-state NMR and structural biology. First, sample handling represents a maj...
Technologies for Solid-State NMR Data Collection
TR&D 2 SUMMARY The overall performance of the NMR spectrometer impacts every research sample and outcome. Often for complex multidimensional magic-angle spinning solid-state NM...