Results for Health
130,725 grants found
Showing 125,861 – 125,880 of 130,725 grants for "Health"
Feasibility of Objective Measures and Outpatient Washout in Disease-Modifying Trials for Parkinson's Disease
PROJECT SUMMARY AND CAREER DEVELOPMENT ABSTRACT There is no therapy that slows the progression of any symptom of Parkinson’s disease (PD), a progressive, age-related neurodegenerat...
A High-Speed, User-Friendly, Handheld OCT System for Patients who are Unable to Cooperate
ABSTRACT Optical coherence tomography (OCT) is the gold standard for the diagnosis and monitoring of retinal and optic nerve diseases. Clinical OCT systems (large tabletop devices...
Xenon MRI in Pulmonary Hypertension
ABSTRACT The diagnosis and follow-up of patients with pulmonary arterial hypertension (PAH) continues to be challenging, with a lack of unambiguous biomarkers that reflect the cour...
Feasibility of Objective Measures and Outpatient Washout in Disease-Modifying Trials for Parkinson's Disease
PROJECT SUMMARY AND CAREER DEVELOPMENT ABSTRACT There is no therapy that slows the progression of any symptom of Parkinson’s disease (PD), a progressive, age-related neurodegenerat...
Xenon MRI in Pulmonary Hypertension
ABSTRACT The diagnosis and follow-up of patients with pulmonary arterial hypertension (PAH) continues to be challenging, with a lack of unambiguous biomarkers that reflect the cour...
Juntas Adelante: A Peer-coaching Intervention to Promote Chemoprophylaxis for HIV Prevention among Latina Transgender Women in the Washington DC Metropolitan Area
PROJECT SUMMARY/ABSTRACT Transgender women (TW) bear a disproportionate burden of HIV, with one of the single largest HIV-related disparities found among Latina TW, whose HIV preva...
Pancreatic Neural Circuitry in Obesity and Diabetes
Project Summary/Abstract: Obesity is extremely prevalent in the United States, and linear trend forecasts suggest that more than 50% of the population will suffer from obesity by 2...
Blood Pressure, Obesity, and Diabetes in Relation to Perinatal and Postpartum Complications
PROJECT SUMMARY/ABSTRACT Hypertensive disorders in pregnancy (HDP) are a leading cause of maternal morbidity, affecting over 350,000 pregnant U.S. women annually. HDP rates increas...
Exploring Common Biological Pathways Underlying Insulin Resistance and Alzheimer Disease using Genetic and Omic Tools
Project Summary / Abstract Insulin resistance (IR) is a major risk factor for Alzheimer’s disease (AD) but the mechanisms by which IR predisposes to AD is unknown, notably, if IR i...
CAREER: Addressing Algorithmic Challenges in Computational Genomic Epidemiology
Fighting viral epidemics is one of the major challenges faced by the modern globally connected world. Recent technological advances had a profound effect on our answers to that cha...
CAREER: Closing the Rural Water and Education Gap with a Simple Advanced Oxidation Process
Drinking water pollution is a major public health concern. Some organic pollutants of drinking water are not easily treated by the commonly used techniques of filtration and chlori...
Stories in Transition: Examining the role of arts, culture and sport in supporting veteran transition to civilian life
The Stories in Transition project pioneers creative methods to co-produce research with veterans about the role of arts, sport and culture activities in supporting military-to-civi...
Spermidine as a New Therapy for Colitis and Chemopreventive for Colitis-associated Carcinogenesis
SUMMARY: Inflammatory bowel disease (IBD) afflicts over three million people in the USA, is increasing worldwide, and leads to colitis-associated carcinogenesis (CAC).We are seekin...
Spermidine as a New Therapy for Colitis and Chemopreventive for Colitis-associated Carcinogenesis
SUMMARY: Inflammatory bowel disease (IBD) afflicts over three million people in the USA, is increasing worldwide, and leads to colitis-associated carcinogenesis (CAC). We are seeki...
An investigation into the experiences of domestic abuse helpline staff and service users during COVID-19 lockdown
Mobility restrictions enforced by the UK Government in since the beginning of the Covid-19 pandemic in March 2020 have resulted in those vulnerable to domestic abuse being confined...
Human TfR1-expressing hamsters to model New World arenaviral hemorrhagic fever
PROJECT SUMMARY Mammarenaviruses are endemic in rodent populations worldwide and their zoonotic transmission can lead to a severe life-threatening hemorrhagic fever (HF) syndrome....
Home-Based Self-Management of Chronic Pain in Adults with Sickle Cell Disease: Applying a Biopsychosocial and Technological Approach
PROJECT SUMMARY/ABSTRACT.In adults with sickle cell disease (SCD), chronic pain is associated with substantial morbidity, mortality, and healthcare utilization.The incidence of chr...
Home-Based Self-Management of Chronic Pain in Adults with Sickle Cell Disease: Applying a Biopsychosocial and Technological Approach
PROJECT SUMMARY/ABSTRACT. In adults with sickle cell disease (SCD), chronic pain is associated with substantial morbidity, mortality, and healthcare utilization. The incidence of c...
Integrative Genomics into Genetic Association Studies of Blood Pressure and Stroke in African Americans
PROJECT SUMMARY Stroke is the third leading cause of death among African Americans (AAs): they are twice as likely to die from stroke as European Americans (EAs), and their inciden...
Determinants of induced Treg and inflammatory Th17 cell balance in response to potentially pathogenic microbiota
Interactions of the gut microbiota with cells of the immune system govern multiple physiological functions that are manifested locally, in the regulation of intestinal barrier func...