Results for Health
130,725 grants found
Showing 125,881 – 125,900 of 130,725 grants for "Health"
Illuminating Druggable Targets via Interrogation of Direct GPCR-kinase Interactions
Illuminating Druggable Targets via Interrogation of Direct GPCR-kinase Interactions G protein-coupled receptors (GPCRs) and kinases represent two of the most highly druggable class...
Determinants of induced Treg and inflammatory Th17 cell balance in response to potentially pathogenic microbiota
Interactions of the gut microbiota with cells of the immune system govern multiple physiological functions that are manifested locally, in the regulation of intestinal barrier func...
Determinants of induced Treg and inflammatory Th17 cell balance in response to potentially pathogenic microbiota
Interactions of the gut microbiota with cells of the immune system govern multiple physiological functions that are manifested locally, in the regulation of intestinal barrier func...
Investigating the Role of GDE2 in Neuronal Mitotic Inhibition and Nuclear Pore Complex Defects
Project Summary / Abstract Alzheimer's disease (AD) and related diseases (ADRDs) are the leading cause of dementia, affecting millions of people each year. Despite being such...
Characterization of a human-specific positive regulator of flavivirus infection
Project Summary/Abstract Flaviviruses such as yellow fever virus (YFV), Zika virus (ZIKV) or Dengue virus (DENV) are cause of great health and economic concerns worldwide.YFV is th...
Characterization of a human-specific positive regulator of flavivirus infection
Project Summary/Abstract Flaviviruses such as yellow fever virus (YFV), Zika virus (ZIKV) or Dengue virus (DENV) are cause of great health and economic concerns worldwide. YFV is t...
Limited Competition: Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in The Young Study (TEDDY)
Project Summary/Abstract The University of South Florida is uniquely qualified to conduct the activities specified in this limited competition RFA. The purpose of the RFA is to fun...
Rapid point-of-care detection of Chlamydia trachomatis in urine
Project Summary The goal of this project is to demonstrate feasibility of a system for the point-of-care (POC) detection of Chlamydia trachomatis (CT) in human urine samples that i...
Telemedicine for Pediatric Sickle Cell Care in Medically Underserved Communities
Sickle cell disease (SCD) is the most common inherited hematologic disease. Studies have shown that comprehensive medical care can decrease adverse outcomes associated with SCD, bu...
Longitudinal Relationships Among Sleep, Cognition and Alzheimer's Disease Biomarkers: Discerning Causal Associations, Mediators and Susceptibility
As the population has aged, there has been a staggering increase in the prevalence and morbidity of cognitive impairment and Alzheimer's disease (AD) related dementias (ADRD):...
Sleep-dependent synaptic homeostasis in Alzheimer's disease
PROJECT SUMMARY Sleep is an essential conserved behavior seen throughout life and is critical for brain health and maintenance of cognitive functions such as learning and memory. S...
REU Site: The future of discovery: training students to build and apply open source machine learning models and tools
Machine learning is a powerful tool that has been successfully applied to a variety of problems that until recently were deemed too difficult or impossible for computers to solve....
Investigating the Role of GDE2 in Neuronal Mitotic Inhibition and Nuclear Pore Complex Defects
Project Summary / Abstract Alzheimer's disease (AD) and related diseases (ADRDs) are the leading cause of dementia, affecting millions of people each year.Despite being such a...
Differential Brain-Region Specific Roles of CASK in Optic Nerve Hypoplasia and Pontocerebellar Hypoplasia
PROJECT SUMMARY Understanding how different regions of the central nervous system (CNS) are affected by genetic insults is critical to advancing the study of CNS pathologies which...
Investigating the Role of GDE2 in Neuronal Mitotic Inhibition and Nuclear Pore Complex Defects
Project Summary / Abstract Alzheimer's disease (AD) and related diseases (ADRDs) are the leading cause of dementia, affecting millions of people each year. Despite being such...
Methionyl-tRNA Synthetase inhibitors can be developed as novel Giardiasis therapeutics
Project Summary/Abstract Giardia lamblia is the causative agent of giardiasis, a gastrointestinal illness with symptoms including diarrhea and malabsorption. Chronic infections can...
Methionyl-tRNA Synthetase inhibitors can be developed as novel Giardiasis therapeutics
Project Summary/Abstract Giardia lamblia is the causative agent of giardiasis, a gastrointestinal illness with symptoms including diarrhea and malabsorption. Chronic infections can...
Methionyl-tRNA Synthetase inhibitors can be developed as novel Giardiasis therapeutics
Project Summary/Abstract Giardia lamblia is the causative agent of giardiasis, a gastrointestinal illness with symptoms including diarrhea and malabsorption. Chronic infections can...
Cross-regulation of Immunometabolism and Circadian Pathways in Obesity Pathophysiology
Project Summary Obesity and diabetes are increased among individuals subjected to shiftwork, reduced sleep, and social jetlag. High fat diet (HFD) misaligns intrinsic circadian cyc...
Methionyl-tRNA Synthetase inhibitors can be developed as novel Giardiasis therapeutics
Project Summary/Abstract Giardia lamblia is the causative agent of giardiasis, a gastrointestinal illness with symptoms including diarrhea and malabsorption.Chronic infections can...