Results for Health
130,725 grants found
Showing 125,981 – 126,000 of 130,725 grants for "Health"
Social spatial navigation assessment for early-stage Alzheimer's disease
Project Summary Alzheimer’s disease (AD) is a public health epidemic, laying an enormous mental, physical, and financial burden on individuals, families, and societies. Despite sig...
The role of RGS12 in differential modulation of G protein versus beta-arrestin signaling downstream of the kappa opioid receptor
The kappa opioid receptor (KOR) helps mediate responses to stress, yet is also implicated in developing and/or maintaining health disorders of chronic pain, drug addiction, anxiety...
Limited Competition: Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in The Young Study (TEDDY)
Project Summary/Abstract The University of South Florida is uniquely qualified to conduct the activities specified in this limited competition RFA.The purpose of the RFA is to fund...
Limited Competition: Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in The Young Study (TEDDY)
Project Summary/Abstract The University of South Florida is uniquely qualified to conduct the activities specified in this limited competition RFA. The purpose of the RFA is to fun...
TestEd: Developing and evaluating an affordable whole-system approach for early detection of viral infections in workplaces and communities
The TestEd programme at the University of Edinburgh will develop and evaluate an affordable whole system approach for early detection of COVID-19 that will provide a blueprint for...
Care, Inequality & Wellbeing in Transnational Families in Europe: a transnational intergenerational study in Spain, France, Sweden & UK (CAREWELL-TF)
This innovative transnational research project will investigate the relationships between care, inequalities & wellbeing among different generations of transnational families i...
Myeloid Malignancy Variant Curation Expert Panel
Germline predisposition to hematopoietic malignancies is more common than previously appreciated and is best understood currently for the myeloid malignancies. Variants in genes su...
Correlates of protective immunity to HCV and rational vaccine design: Project 1
Project 1: High resolution profiling of protective HCV-specific CD4 T cells Abstract Hepatitis C virus (HCV) is a virus that infects the liver and is transmitted through contaminat...
Sleep-dependent synaptic homeostasis in Alzheimer's disease
PROJECT SUMMARY Sleep is an essential conserved behavior seen throughout life and is critical for brain health and maintenance of cognitive functions such as learning and memory.Sl...
Role of maternal Treg cells in the induction of neonatal tolerance
Project Summary Food allergy (FA) is a growing public health concern.The effects of maternal immune responses on the induction of regulatory T (Treg) cell-mediated tolerance in off...
Applying pathomics to establish a biosignature for aggressive skin melanoma
PROJECT SUMMARY We propose to develop a pathomics biosignature for aggressive melanoma to guide treatment decisions for patients who have had a melanoma surgically removed but rema...
University of Rochester Vaccine and Treatment Evaluation Unit (VTEU)
The Vaccine and Treatment Evaluation Units (VTEUs) are a critical resource for the NIAID Infectious Diseases Clinical Research Consortium to conduct clinical research and trials to...
Applying pathomics to establish a biosignature for aggressive skin melanoma
PROJECT SUMMARY We propose to develop a pathomics biosignature for aggressive melanoma to guide treatment decisions for patients who have had a melanoma surgically removed but rema...
Testing the usability of a web-based hypospadias decision aid for parents using a user-centered design approach
Reconstructive surgery is advocated for most children with hypospadias to prevent potentially serious cosmetic and functional problems.Parents faced with a decision about hypospadi...
Establishing Behavioral and Biological Predictors of Problematic Cannabis Use
PROJECT SUMMARY The recent wave of recreational cannabis legalization in the US has left many concerned that rates of cannabis dependence and cannabis use disorder (CUD) will rise...
Smartphone Pupillometer for At-Home Screening for Risk of Alzheimer’s Disease
Project Summary/Abstract Dementia represents one of the most important public health concerns in the coming decades.Among the most important research goals will be to identify the...
Telemedicine for Pediatric Sickle Cell Care in Medically Underserved Communities
Sickle cell disease (SCD) is the most common inherited hematologic disease. Studies have shown that comprehensive medical care can decrease adverse outcomes associated with SCD, bu...
ANALYSIS OF INTRAHEPATIC MACROPHAGE PROFILES FOR PREDICTING RISK OF FIBROSIS DEVELOPMENT IN PATIENTS WITH DIFFERENT TYPES OF CHRONIC LIVER DISEASE
PROJECT SUMMARY/ABSTRACT Cirrhosis and hepatocellular carcinoma are increasing health and economic burdens. Non-alcoholic fatty liver disease (NAFLD/NASH), alcohol-associated liver...
Development of 4D Flow MRI for Risk Stratification of Variceal Bleeding in Cirrhosis
PROJECT SUMMARY: The overarching goal of our research is to improve the management and health of an estimated 1 million Americans suffering from end-stage liver disease (cirrhosis)...
Microbial and Host Factors that Promote Epithelial Disruption and S. pneumoniae Transit out of the Lung
Project Summary Streptococcus pneumoniae causes ~900,000 cases of pneumococcal pneumonia annually in the US, with a mortality rate of 5-7%, making this disease a major health and f...