Results for Health
130,725 grants found
Showing 126,021 – 126,040 of 130,725 grants for "Health"
Federal School Nutrition Policies, Student Food Insecurity and BMI
Project Abstract Food insecurity increased since COVID-19 and children who are food insecure are at increased risk of physical and mental health disorders.In response to pandemic-r...
Evaluating Human Cochlear Aging Using Otoacoustic Emissions (OAEs)
PROJECT SUMMARY/ABSTRACT Age-related hearing loss (ARHL) affects millions of individuals in the U.S. and is associated with devastating health and economic outcomes. A primary site...
Regulation of DNA Replication Timing by Origin Recognition Complex (ORC) Phosphorylation
PROJECT SUMMARY Successful duplication of the genome requires the accurate replication of billions of bases. Failure to do so results in genomic instability and ultimately a host o...
Mechanistic study of Small-molecular Therapy in diabetic Wound Healing
Diabetic foot ulcers that lead to amputations are a major health problem affecting ~20% of the 30 million diabetic patients in the US. The current regimen has limited success, and...
Identifying the Long-Term Neurological Effects of COVID-19 Using 7 Tesla Multi-Modal MRI
Project Summary A growing body of evidence indicates that COVID-19 has neurological manifestations, many of which may persist post-infection. 36% to 67% of COVID-19 patients develo...
Rational design of a safe recombinant Candid#1 vaccine
Arenaviruses are endemic in rodent populations and can be transmitted to humans to cause severe life- threatening hemorrhagic fevers. Relevant US agencies (DHHS, DHS and DoD) and t...
Mechanisms of cysteinyl leukotriene receptor 2 (CysLT2R)-mediated signaling and migration in melanocytes and uveal melanoma
PROJECT SUMMARY (ABSTRACT) Melanocytes comprise a heterogeneous group of neural crest-derived cells that are present in the skin, eyes, ear, heart, and brain. While the function of...
Evaluating Human Cochlear Aging Using Otoacoustic Emissions (OAEs)
PROJECT SUMMARY/ABSTRACT Age-related hearing loss (ARHL) affects millions of individuals in the U.S. and is associated with devastating health and economic outcomes. A primary site...
The Impact of Early Life Stress on Reward and Body Weight
PROJECT SUMMARY My long-term professional goal is to become a successful, independent scientist with a research program focused on obesity and the neurobiological regulation of fee...
Quantification of Liver Fibrosis with MRI and Deep Learning
Project Summary/Abstract Chronic liver disease (CLD) is a common cause of morbidity and mortality in the U.S. and throughout the world. In 2017, CLD had an age-adjusted death rate...
Microbial and Host Factors that Promote Epithelial Disruption and S. pneumoniae Transit out of the Lung
Project Summary Streptococcus pneumoniae causes ~900,000 cases of pneumococcal pneumonia annually in the US, with a mortality rate of 5-7%, making this disease a major health and f...
Trajectories of socially regulated gene expression, methamphetamine use, and viral load among HIV-positive men who have sex with men (MSM) receiving contingency management
PROJECT ABSTRACT The K01 Mentored Research Scientist Development Award will provide Dr. Michael Li with invaluable research experience, mentored training from interdisciplinary fac...
Rational design of a safe recombinant Candid#1 vaccine
Arenaviruses are endemic in rodent populations and can be transmitted to humans to cause severe life- threatening hemorrhagic fevers. Relevant US agencies (DHHS, DHS and DoD) and t...
Blood Pressure, Obesity, and Diabetes in Relation to Perinatal and Postpartum Complications
PROJECT SUMMARY/ABSTRACT Hypertensive disorders in pregnancy (HDP) are a leading cause of maternal morbidity, affecting over 350,000 pregnant U.S. women annually. HDP rates increas...
ANALYSIS OF INTRAHEPATIC MACROPHAGE PROFILES FOR PREDICTING RISK OF FIBROSIS DEVELOPMENT IN PATIENTS WITH DIFFERENT TYPES OF CHRONIC LIVER DISEASE
PROJECT SUMMARY/ABSTRACT Cirrhosis and hepatocellular carcinoma are increasing health and economic burdens. Non-alcoholic fatty liver disease (NAFLD/NASH), alcohol-associated liver...
Translational Approaches to Mitigate Enhanced Alzheimer’s Disease Risk Following a Mild TBI
ABSTRACT A traumatic brain injury (TBI) is a well-known risk factor for Alzheimer's disease. There is not a one-to-one relationship, where a TBI will lead to the development o...
Trajectories of socially regulated gene expression, methamphetamine use, and viral load among HIV-positive men who have sex with men (MSM) receiving contingency management
PROJECT ABSTRACT The K01 Mentored Research Scientist Development Award will provide Dr. Michael Li with invaluable research experience, mentored training from interdisciplinary fac...
Exploring Common Biological Pathways Underlying Insulin Resistance and Alzheimer Disease using Genetic and Omic Tools
Project Summary / Abstract Insulin resistance (IR) is a major risk factor for Alzheimer’s disease (AD) but the mechanisms by which IR predisposes to AD is unknown, notably, if IR i...
ANALYSIS OF INTRAHEPATIC MACROPHAGE PROFILES FOR PREDICTING RISK OF FIBROSIS DEVELOPMENT IN PATIENTS WITH DIFFERENT TYPES OF CHRONIC LIVER DISEASE
PROJECT SUMMARY/ABSTRACT Cirrhosis and hepatocellular carcinoma are increasing health and economic burdens. Non-alcoholic fatty liver disease (NAFLD/NASH), alcohol-associated liver...
Exploring Common Biological Pathways Underlying Insulin Resistance and Alzheimer Disease using Genetic and Omic Tools
Project Summary / Abstract Insulin resistance (IR) is a major risk factor for Alzheimer’s disease (AD) but the mechanisms by which IR predisposes to AD is unknown, notably, if IR i...