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Results for Health

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Showing 126,061126,080 of 130,725 grants for "Health"

Completed NON-SBIR/STTR RPGS
Locating the neural substrates for the flexor synergy after stroke
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... University of Newcastle United Kingdom 2021 – 2026

A stroke often damages motor areas of the brain.Understandably, this leads to a loss of movement control: the limbs become weak, and movements are slower and less well-coordinated....

$4.6M
USD
Completed NON-SBIR/STTR RPGS
Locating the neural substrates for the flexor synergy after stroke
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... University of Newcastle United Kingdom 2021 – 2026

A stroke often damages motor areas of the brain. Understandably, this leads to a loss of movement control: the limbs become weak, and movements are slower and less well-coordinated...

$4.58M
USD
Completed NON-SBIR/STTR RPGS
Determinants of induced Treg and inflammatory Th17 cell balance in response to potentially pathogenic microbiota
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... New York University School of Medicine United States 2021 – 2026

Interactions of the gut microbiota with cells of the immune system govern multiple physiological functions that are manifested locally, in the regulation of intestinal barrier func...

$5.21M
USD
Completed NON-SBIR/STTR RPGS
Locating the neural substrates for the flexor synergy after stroke
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... University of Newcastle United Kingdom 2021 – 2026

A stroke often damages motor areas of the brain. Understandably, this leads to a loss of movement control: the limbs become weak, and movements are slower and less well-coordinated...

$4.58M
USD
Completed NON-SBIR/STTR RPGS
Locating the neural substrates for the flexor synergy after stroke
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... University of Newcastle United Kingdom 2021 – 2026

A stroke often damages motor areas of the brain. Understandably, this leads to a loss of movement control: the limbs become weak, and movements are slower and less well-coordinated...

$4.44M
USD
Completed NON-SBIR/STTR RPGS
Cytolethal Distending Toxin and Intestinal Homeostasis
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Illinois At Urbana-Champai... United States 2021 – 2023

Our long-term goal is to understand how pathogen-mediated genotoxicity, which is increasingly associated with pathogenic bacteria, fungi, and viruses, impacts microbe-host interact...

$1.81M
USD
Completed NON-SBIR/STTR RPGS
Preclinical development of a vaccine for Nipah virus
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Texas Med Br Galveston United States 2021 – 2026

PROJECT SUMMARY/ABSTRACT Nipah virus (NiV) causes febrile encephalitis and severe respiratory disease in humans with fatality rates as high as 100% in some outbreaks (average ~ 75%...

$11.8M
USD
Active NON-SBIR/STTR RPGS
Preclinical development of a vaccine for Nipah virus
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Texas Med Br Galveston United States 2021 – 2027

PROJECT SUMMARY/ABSTRACT Nipah virus (NiV) causes febrile encephalitis and severe respiratory disease in humans with fatality rates as high as 100% in some outbreaks (average ~ 75%...

$11.59M
USD
Completed NON-SBIR/STTR RPGS
Osteoblast Dopamine Receptor Mediates Diabetic Bone Disease
NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETA... Ada Forsyth Institute, Inc United States 2021 – 2023

Abstract Diabetes is estimated to affect at least 100 million people in the United States. Diabetic bone disease is a complication of both type 1 and type 2 diabetes.Diabetic bone...

$2.63M
USD
Completed NON-SBIR/STTR RPGS
Cytolethal Distending Toxin and Intestinal Homeostasis
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Illinois At Urbana-Champai... United States 2021 – 2024

Our long-term goal is to understand how pathogen-mediated genotoxicity, which is increasingly associated with pathogenic bacteria, fungi, and viruses, impacts microbe-host interact...

$2.21M
USD
Completed NON-SBIR/STTR RPGS
Nutrition and Physical Activity Assessment Study - Assessment of Dietary Supplements
NATIONAL CANCER INSTITUTE Fred Hutchinson Cancer Research Center United States 2021 – 2021

ABSTRACT We are responding to PA-20-227 ?Administrative Supplement for Research on Dietary Supplements? to support dietary supplement-related analysis of previously collected data...

$1.76M
USD
Completed NON-SBIR/STTR RPGS
Development of human adaptive immunity to Staphylococcus aureus
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Washington University United States 2021 – 2026

Staphylococcus aureus is an aggressive antibiotic-resistant human bacterial pathogen.S. aureus is a leading cause of infectious disease morbidity, mortality, and hospital-associate...

$6.44M
USD
Completed NON-SBIR/STTR RPGS
Development of human adaptive immunity to Staphylococcus aureus
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Washington University United States 2021 – 2026

Staphylococcus aureus is an aggressive antibiotic-resistant human bacterial pathogen.S. aureus is a leading cause of infectious disease morbidity, mortality, and hospital-associate...

$6.28M
USD
Completed NON-SBIR/STTR RPGS
Estimating the risk for and severity of respiratory infections attributable to CFTR heterozygosity
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Iowa United States 2021 – 2026

Project Summary/Abstract 1 Cystic fibrosis is one of the most common autosomal regressive genetic disorders in the United States: 2 approximately 1 out of 32 Caucasians and 1 out o...

$7.65M
USD
Completed OTHER RESEARCH-RELATED
Trajectories of socially regulated gene expression, methamphetamine use, and viral load among HIV-positive men who have sex with men (MSM) receiving contingency management
NATIONAL INSTITUTE ON DRUG ABUSE University of California Los Angeles United States 2021 – 2026

PROJECT ABSTRACT The K01 Mentored Research Scientist Development Award will provide Dr. Michael Li with invaluable research experience, mentored training from interdisciplinary fac...

$1.89M
USD
Completed NON-SBIR/STTR RPGS
Osteoblast Dopamine Receptor Mediates Diabetic Bone Disease
NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETA... Ada Forsyth Institute, Inc United States 2021 – 2024

Abstract Diabetes is estimated to affect at least 100 million people in the United States. Diabetic bone disease is a complication of both type 1 and type 2 diabetes. Diabetic bone...

$2.17M
USD
Completed NON-SBIR/STTR RPGS
Quantification of HIV burden and the biomedical, structural, and behavioral factors influencing HIV/AIDS among children and young adolescents
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Washington United States 2021 – 2026

PROJECT SUMMARY/ABSTRACT HIV/AIDS is a leading cause of morbidity and mortality among children and adolescents, and it is well recognized that HIV care and treatment among children...

$6.96M
USD
Completed NON-SBIR/STTR RPGS
ANALYSIS OF INTRAHEPATIC MACROPHAGE PROFILES FOR PREDICTING RISK OF FIBROSIS DEVELOPMENT IN PATIENTS WITH DIFFERENT TYPES OF CHRONIC LIVER DISEASE
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... University of Texas Med Br Galveston United States 2021 – 2026

PROJECT SUMMARY/ABSTRACT Cirrhosis and hepatocellular carcinoma are increasing health and economic burdens. Non-alcoholic fatty liver disease (NAFLD/NASH), alcohol-associated liver...

$4.13M
USD
Completed NON-SBIR/STTR RPGS
Rational design of a safe recombinant Candid#1 vaccine
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Montana United States 2021 – 2025

Arenaviruses are endemic in rodent populations and can be transmitted to humans to cause severe life- threatening hemorrhagic fevers. Relevant US agencies (DHHS, DHS and DoD) and t...

$3.64M
USD
Completed NON-SBIR/STTR RPGS
Preclinical development of a vaccine for Nipah virus
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Texas Med Br Galveston United States 2021 – 2026

PROJECT SUMMARY/ABSTRACT Nipah virus (NiV) causes febrile encephalitis and severe respiratory disease in humans with fatality rates as high as 100% in some outbreaks (average ~ 75%...

$14.16M
USD