Results for Health
130,725 grants found
Showing 126,221 – 126,240 of 130,725 grants for "Health"
Contributions of gastrointestinal Staphylococcus aureus and other gut microbiota to pediatric atopic dermatitis
PROJECT SUMMARY Atopic dermatitis (AD) is the most common inflammatory skin disease in children worldwide and has a substantial detrimental impact on patients’ quality of life. Sta...
Pathobiology of ICH in Aging
ABSTRACT Intracerebral hemorrhage (ICH) leads to severe brain damage, profound deficit, and death in ~40% of patients, and aging is a key risk factor for poor outcome. At least 30%...
INfectious Diseases Summer Program Integrating Research at Emory (INSPIRE)
PROJECT SUMMARY The objective of the proposed INfectious Diseases Summer Program Integrating Research at Emory (INSPIRE) research training program is to prepare undergraduate stude...
Roles of gut-breast axis in breast pathophysiology
Microbiome impacts cancer development and therapeutic efficacy. In addition to the guts, microbes reside in different tissues influencing the pathophysiology of the tissue microenv...
Evaluating the impact of sugar warnings on beverage purchases in Hispanic populations
ABSTRACT Hispanic populations in the US have higher rates of obesity, diabetes, and nonalcoholic fatty liver disease compared to non-Hispanic white populations. These disparities a...
Fostering Underrepresented Employees' Resilience and Zeal for Academia (FUERZA)
Project Summary/Abstract The broad, long-term objectives of the Fostering Underrepresented Employees’ Resilience and Zeal for Aca- demia (FUERZA) project are three-fold. The first...
Neutrophil responses Drive Severe Asthma
PROJECT 2 ABSTRACT: Asthma is the most common chronic lung disease worldwide. Importantly, over half of the $3.1B spent in the U.S. each year on asthma health care costs derive fro...
Choosing Immune Suppression in Renal Transplantation by Efficacy and Morbidity2 (CISTEM2)
Summary/Abstract Kidney transplant (KT) survival faces challenges from increased patient complexity, use of non-standard donors, and longer cold ischemic times. Despite refinement...
Mentoring in Pediatric Cardiovascular Pharmacology and Early Phase Trials
Cardiovascular (CV) therapeutics remain dangerously understudied in children: of 1055 FDA pediatric label changes under BPCA and PREA since 1998, only 29 were in CV drugs, and >...
Cellular reprogramming of cochlear glial cells to regenerate auditory neurons
PROJECT ABSTRACT Sensorineural hearing loss is a major public health issue; by 2050, over 900 million people will have some form of auditory impairment. The spiral ganglion nerve (...
Molecular and cellular mechanisms of neuronal damage caused by anticancer therapies
Project Summary Cancer is a terrifying diagnosis, especially in a child, yet thanks to great advances in treatment, survival rates have increased steeply. For CNS/brain tumors and...
PA-23-189 for Kaya Johnson to CA260126-01: Identifying a proteomic signature for breast cancer detection in breast milk and serum
Program Director/Principal Investigator (Last, First, Middle): Darie, Costel C. Supplement Application (PAR-18-714) for Candidate Kaya Johnson Funded parent grant CA260126-01: Iden...
Developing Pluripotent Stem Cells to Model and Treat Lung Disease
SUMMARY: OVERALL PROGRAM The goal of this Program Project Grant (PPG) is advancing the latest discoveries in stem cell biology, human organoid models, and gene editing to understan...
Low-dose contrast enhanced fast pediatric brain MRI
Project Summary: Brain MRIs are widely used in children for diagnosis and treatment monitoring. A typical exam comprises multiple sequences with different contrast preparations, an...
NSF-BII: Integrative Movement Sciences Institute
Muscle is the active tissue that drives the remarkable agility of animals, enabling feats of speed, endurance, and maneuverability in challenging environments. Understanding how mu...
Lymphatic Endothelial Piezo1-TRPV4 Channel Signaling in Obesity
Obesity is a serious health concern in the US and is a significant risk factor for many causes of mortality, including stroke and cardiovascular disease. Significant evidence point...
From Symbiosis to Dysbiosis and Back: The Impact of Pro-Inflammation and Pro-Resolution
Periodontitis is initiated by oral bacteria, but quickly transits to an inflammatory immune disease with loss of host- bacterial homeostasis. Homeostasis, the symbiotic balance bet...
Integrating Signals in Iron Homeostasis
Iron often limits plant growth and agricultural yield. Furthermore, more than 2 billion people are iron deficient because their plant-based diets are not a rich source of iron, mak...
CAREER: Engineered Hydrogels to Study Host-Parasite Interactions that Drive Extracellular Matrix Remodeling
When certain parasites invade our bodies, they often lead to a peculiar thing – internal organs get larger. In Leishmania infections, even after patients clear out the parasites, t...
NSF Engines Development Award: Developing innovative solutions for next-generation factory-built housing (IN, MI)
This NSF Regional Innovation Engine Development award is focused on further developing and solidifying an ecosystem that can transform the housing industry in the US by scaling up...