Results for Health
130,725 grants found
Showing 126,421 – 126,440 of 130,725 grants for "Health"
Nonsense-mediated mRNA decay and beyond
This MIRA application extends our decades-long research on nonsense-mediated mRNA decay (NMD) and how NMD factors can function in other aspects of cellular metabolism. NMD is a fun...
SCH: Robust Multimodal Longitudinal AI for Enhanced Breast Cancer Screening
The overarching objective of this project is to optimize and personalize breast cancer screening by advancing artificial intelligence (AI) algorithms. Breast cancer is a major glob...
Collaborative Research: OPUS: Synthesizing multi-decadal and multi-site data to promote understanding of key questions in stochastic demography
The geographical ranges of most species across the Earth are made up of multiple populations (all individuals of that species in a defined area) and these populations often experie...
Action in solution: Embedding new technology and new capability in Biomolecular Interactions in the University of Leeds
Life's processes depend on the interactions of macromolecules with ligands and other macromolecules, and the resulting conformational and functional changes that occur upon co...
Multiomic Analysis of Immunotherapy Features Evidencing Success and Toxicity (MANIFEST)
Harnessing the immune system to treat cancer has revolutionised survival outcomes for many patients. Immune checkpoint inhibitor therapies which unleash the brakes from immune cell...
A rapid scanning ion mobility MALDI-TOF mass spectrometry platform for state of the art metabolomics, proteomics and molecular imaging
Mass spectrometry (MS) is a critical analytical technology that underpins a significant research portfolio across the School of Biosciences at The University of Sheffield (TUoS). T...
Brief Digitally-Enhanced Intervention for Managing Emotional Pain and Reducing Alcohol Use during Medication for OUD
ABSTRACT Heavy, problematic alcohol use is highly prevalent within individuals receiving medications for opioid use disorder (MOUD) and contributes to increased risk of opioid over...
CHIPP-PrEP: Cabotegravir-Hormone Interrogation of Pharmacokinetics/Pharmacodynamics for HIV Prevention in Cisgender and Transgender Persons
PROJECT SUMMARY____________________________________________________________________ The goal of CHIPP-PrEP: Cabotegravir-Hormone Interrogation of Pharmacokinetics/Pharmacodynamics...
Probing Molecular Mechanisms of Allosteric Inhibition of HIV-1 Reverse Transcriptase
Project Summary/Abstract HIV remains a major global health issue; strict adherence to combined antiretroviral therapy can reduce a patient's active virus to undetectable level...
In vivo innate immune sensing of HIV-1 infection
SUMMARY/ABSTRACT HIV-1 remains a major public health challenge worldwide, with 1.3 million new infections and over 600,000 AIDS- related deaths in 2022. An effective vaccine that c...
Collaborative Research: OPUS: Synthesizing multi-decadal and multi-site data to promote understanding of key questions in stochastic demography
The geographical ranges of most species across the Earth are made up of multiple populations (all individuals of that species in a defined area) and these populations often experie...
Postdoctoral Fellowship: STEMEdIPRF: Resource Use as a Mediator of Sociodemographic Disparities in Student Success
From office hours, to textbooks, to mental health counseling, the use of resources is essential to undergraduate STEM students’ academic success. Previous work has revealed signifi...
BRITE Pivot: Using Fracture Mechanics to Study Childbirth after an Episiotomy
An episiotomy, in which a doctor or midwife makes a small incision from the back of the vagina through the perineum towards the anus to widen the vaginal opening, is sometimes used...
Collaborative Research: Phenobase: Community, infrastructure, and data for global-scale analyses of plant phenology
Plant phenology – the timing of plant life-cycle events, such as leaf growth, flowering, and fruiting – plays a fundamental role in shaping terrestrial ecosystems. The timing of pl...
Revolutionizing Tuberculosis Diagnostics: A Graphene Oxide-Based Biosensor for Enhanced Sensitivity and Selectivity in Cord Factor Detection
"Bovine tuberculosis is a chronic infectious disease which affects a broad range of mammalian hosts. The disease can be transmitted in several ways; for example, by direct...
Relational Dynamics in Depression: A Process-Philosophical Approach to Phenomenology
ContextThis research will explore the nature of depression, moving beyond clinical and biochemical analysis. There is growing recognition that these conditions should be understood...
Novel machine learning techniques to generate high spatio-temporal resolution urban climate observations for climate adaptation
As cities worldwide expand, urban areas are experiencing rising air and surface temperatures. These temperature increases exacerbate the impacts of climate change, threatening the...
Ion Channels in Perinatal Asphyxia: Understanding the Pathology to Improve Treatment
Perinatal asphyxia often leads to serious health complications and cognitive impairment and is a significant contributor to neonatal mortality. The current treatments for perinatal...
Beyond Oz's Curtain: A Recharacterisation of Monothematic Delusions through Consequential Harm
Monothematic delusions (MDs) are a specific type of delusion characterised as having a single theme (Coltheart,2013). For instance, Cotard delusion is the belief that one is dead o...
Exploring the Impact of Polycystic Ovarian Syndrome (PCOS) on Reproductive Experience and Expectations Through a Feminist and Life Course Approach
Endometriosis is a chronic condition where cells similar to those found in the lining of the uterus are present elsewhere in the body, reacting to the menstrual cycle and causing i...