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Results for Health

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Showing 126,521126,540 of 130,725 grants for "Health"

Active NON-SBIR/STTR RPGS
Study of arenavirus assembly
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Georgia State University United States 2022 – 2027

The devastating impact on public health, global economy and social stability incurred by the COVID-19 pandemic in the last two years has highlighted the importance of basic researc...

$5.4M
USD
Active OTHER RESEARCH-RELATED
Studies on bacteriophages in respiratory diseases
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Stanford University United States 2022 – 2027

PROJECT SUMMARY Dr. Bollyky is a mid-career investigator who has developed a successful, translational research program focused on bacteriophages – viruses that infect bacteria - a...

$1.64M
USD
Active NON-SBIR/STTR RPGS
Study of arenavirus assembly
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Georgia State University United States 2022 – 2027

The devastating impact on public health, global economy and social stability incurred by the COVID-19 pandemic in the last two years has highlighted the importance of basic researc...

$5.4M
USD
Active OTHER RESEARCH-RELATED
Studies on bacteriophages in respiratory diseases
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Stanford University United States 2022 – 2027

PROJECT SUMMARY Dr. Bollyky is a mid-career investigator who has developed a successful, translational research program focused on bacteriophages – viruses that infect bacteria - a...

$1.63M
USD
Active TRAINING, INSTITUTIONAL
Bridges to the Baccalaureate Research Training Program at the University of Kansas/Haskell Indian Nations University
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Kansas Lawrence United States 2022 – 2027

PROJECT SUMMARY The Haskell-KU Bridge V Program supports students from Haskell Indian Nations University who seek to develop careers in biomedical, bioengineering, behavioral and e...

$2.81M
USD
Active RESEARCH CENTERS
Pragmatic Trial
NATIONAL CANCER INSTITUTE Sloan-Kettering Inst Can Research United States 2022 – 2027

PROJECT SUMMARY/ABSTRACT The centerpiece of the MATCHES Center is a pragmatic trial, MATCH-UP (MAking Telehealth-delivery of Cancer Care at Home—Upscaled Services Protocol), which...

Active RESEARCH CENTERS
Clinical Practice Network
NATIONAL CANCER INSTITUTE Sloan-Kettering Inst Can Research United States 2022 – 2027

PROJECT SUMMARY/ABSTRACT The purpose of the Clinical Practice Network (CPN) of the MATCHES Telehealth Research Center is to provide the environment for conducting and evaluating th...

Active NON-SBIR/STTR RPGS
Elucidating the mechanisms and consequences of MDSC-regulated immunity in TB
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Pittsburgh At Pittsburgh United States 2022 – 2027

PROJECT SUMMARY: Myeloid derived suppressor cells (MDSCs) are immature myeloid cells with potent inhibitory properties for macrophages and T cells. The link between MDSCs and tuber...

$5.48M
USD
Active NON-SBIR/STTR RPGS
Elucidating the mechanisms and consequences of MDSC-regulated immunity in TB
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Pittsburgh At Pittsburgh United States 2022 – 2027

PROJECT SUMMARY: Myeloid derived suppressor cells (MDSCs) are immature myeloid cells with potent inhibitory properties for macrophages and T cells. The link between MDSCs and tuber...

$6.04M
USD
Completed OTHER RESEARCH-RELATED
Implementation of emergency department screening to impact rising syphilis rates in vulnerable populations
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Chicago United States 2022 – 2026

PROJECT SUMMARY Syphilis rates in the U.S. have been increasing steadily since 2001, with more than 130,000 new cases reported in 2019. Left untreated, syphilis can lead to neurolo...

$1.86M
USD
Completed SBIR-STTR RPGS
VenomSquad: Building skills and interest in STEM with collaborative augmented reality
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Killer Snails Llc United States 2022 – 2024

American students perform at a lower level and express less interest in STEM than students in other countries (Fayer et al., 2017). Additionally, Women, Black, Indigenous, and Peop...

$8.28M
USD
Completed SBIR-STTR RPGS
VenomSquad: Building skills and interest in STEM with collaborative augmented reality
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Killer Snails Llc United States 2022 – 2024

American students perform at a lower level and express less interest in STEM than students in other countries (Fayer et al., 2017). Additionally, Women, Black, Indigenous, and Peop...

$5.69M
USD
Completed NON-SBIR/STTR RPGS
Quantifying and Understanding Glaucoma Eye Drop Medication Instillation and Adherence
NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOEN... University of Michigan At Ann Arbor United States 2022 – 2026

PROJECT ABSTRACT Despite the availability of effective treatments, glaucoma remains the leading cause of irreversible blindness among African American adults and the second leading...

$5.47M
USD
Active OTHER RESEARCH-RELATED
Examining how the novel S64F MAFA variant produces glucose intolerance or hypoglycemia in a sex-dependent manner
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Vanderbilt University Medical Center United States 2022 – 2027

PROJECT ABSTRACT As of 2018, 30.3 million Americans have been diagnosed with diabetes (10% of the U.S. population with a male sex bias). Its close associations with many chronic di...

$1.58M
USD
Active NON-SBIR/STTR RPGS
A novel psychological-behavioral intervention to promote physical activity in type 2 diabetes.
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Massachusetts General Hospital United States 2022 – 2027

Among the 30 million Americans with type 2 diabetes (T2D), physical activity is prospectively associated with better glycemic control, reduced cardiovascular risk, and lower rates...

$6.96M
USD
Active NON-SBIR/STTR RPGS
Staphylococcus aureus SPREAD (S. aureus Study of Prevalence Resistance and Environmental Dissemination)
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Pennsylvania United States 2022 – 2027

PROJECT SUMMARY Staphylococcus aureus is a bacterial species that causes infections of the skin, lungs, blood and internal organs. These infections can have their onset in the comm...

$7.41M
USD
Active NON-SBIR/STTR RPGS
A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure for Individuals on TLD in Sub-Saharan Africa
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Massachusetts General Hospital United States 2022 – 2027

PROJECT SUMMARY Significance: Tenofovir, lamivudine, and dolutegravir (TLD) has become the predominant first-line antiretroviral therapy (ART) regimen in sub-Saharan Africa (SSA)....

$6.43M
USD
Active NON-SBIR/STTR RPGS
Investigation and application of hydrocarbon-degrading enzymes using cryo-electron microscopy and directed evolution
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Michigan State University United States 2022 – 2026

PROJECT SUMMARY Glycyl radical enzymes (GREs) are a growing superfamily that catalyzes an impressive array of chemical transformations critical to both human health and the environ...

$2.49M
USD
Completed NON-SBIR/STTR RPGS
How beta-catenin expands Foxp3+RORgammat+ Pro-inflammatoryT-regulatory cells - Renewal
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Mayo Clinic Arizona United States 2022 – 2025

ABSTRACT The plasticity and functional diversity of regulatory T cells (Tregs) is essential for the maintenance of healthy immunity but it is also exploited in disease. We have des...

$6.49M
USD
Completed NON-SBIR/STTR RPGS
Molecular Neurogenetics of the Brainstem Neuronal Source of Cardioprotective Vagal Outflow
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Thomas Jefferson University United States 2022 – 2026

We aim to identify, predict and control the central brainstem neurons that integrate interoceptive inputs to produce and determine the activity of the vagus nerve in regulating the...

$5.6M
USD