Results for Health
130,725 grants found
Showing 126,721 – 126,740 of 130,725 grants for "Health"
Anatomic microniches and their contribution to vascular remodeling in pulmonary hypertension
Pulmonary hypertension (PH) is a poorly understood disease that causes pathologic remodeling of the smaller diameter vessels of the lung, leading to progressive heart failure. This...
Geometric Deep Learning for Binding Affinity Prediction
Drug discovery is an incredibly expensive and time-consuming process.The average cost of bringing a drug to market is $1.3 billion, which is doubling every nine years, and takes te...
The Influence of Disruptive Technologies on the Resilient and Sustainable Performance of Agri-Food Supply Chains in the Face of COVID-19 Pandemic
Over the years, there has been an increase in the demand for agri-food products, specifically perishable agricultural products such as fresh produce, dairy products, meats, fruits...
TuberSense - Early detection of potato diseases through volatile sensing to reduce food waste in the supply chain
The Food and Agriculture Organisation of the United Nations (FAO) estimate the need to feed a total of 9 billion people by 2050, a task that becomes especially challenging when con...
Driving Simulator for Connected Autonomous Vehicles
According to the World Health Organisation, the number of traffic accident-related deaths remains unacceptably high, with over 1.3 million people dying each year globally. This num...
An intervention: Bullying and banter in male youth community football
BackgroundWith 3.35 million children aged 5-15 participating across England (The FA, 2015), football has facilitated holistic health benefits (Krustrup et al., 2010). However, a bu...
Biocatalytic Synthesis of Selectively Isotopically Labelled Biomolecules for Preparation of Labelled Proteins & NMR Structure Determination
Nuclear magnetic resonance (NMR) is a spectroscopic technique which enables study of the structure and dynamics of proteins in solution, complementing crystallographic and electron...
Zero Emissions Ammonia Power Technology
The broad context behind this research topic is based on the imminent need to transition away from conventional fossil fuels in the transportation sector. Indeed, the urgency to ad...
Antigenic variation of Mycoplasma genitalium during persistent genital tract infection of pig-tailed macaques
PROJECT SUMMARY Mycoplasma genitalium (MG), a sexually transmitted bacterial pathogen, is increasingly recognized as a significant public health concern. The prevalence of MG range...
III: Medium: A Data-driven and AI-augmented Framework for Collaborative Decision Making to Combat Infectious Disease Outbreaks
Infectious disease outbreaks, such as the novel coronavirus disease (COVID-19) pandemic, entailed localized conditions with evolution in time and space present a daunting task for...
Anatomic microniches and their contribution to vascular remodeling in pulmonary hypertension
Pulmonary hypertension (PH) is a poorly understood disease that causes pathologic remodeling of the smaller diameter vessels of the lung, leading to progressive heart failure. This...
Assessing vascular permeability and nanobubble extravasation with contrast-enhanced ultrasound imaging
PROJECT SUMMARY In many chronic inflammatory diseases, vascular endothelial cells become pathologically permeable due to conditions like angiogenesis and production of growth facto...
Unraveling the role of endothelium in chemotherapy-induced cardiotoxicity
Project Summary/Abstract Doxorubicin is a highly effective chemotherapy drug commonly used to treat multiple cancers, but its use is limited due to cardiotoxicity. Cardiotoxicity c...
Ovarian Cancer Detection with Blood- and Imaging-Based Biomarkers
A central problem in ovarian cancer is late diagnosis, which causes the 5-year survival rate to plummet below 50%. Ovarian cancer symptoms are vague and nonspecific, and current sc...
Lung epithelial cell reprogramming by CD4 T cells
PROJECT SUMMARY Candidate Information: I am a postdoctoral fellow in Dr. Joseph Mizgerd’s lab at Boston University Pulmonary Center since Jan-2018 and my work has focused on elucid...
Optimization and validation of quantitative birefringence microscopy for assessment of myelin pathologies associated with cognitive impairments and motor deficits in young and old aging monkey brain
Degeneration or breakdown of the myelin sheath that wraps and insulates axons of the central nervous system, as well as peripheral nerves, is a factor in a large array of neurologi...
Seizures and Children's Outcomes after Stroke (SCOUTS)
PROJECT SUMMARY/ABSTRACT Epilepsy is one of the common problems that can result after ischemic stroke in a child. Children with post- stroke epilepsy have poorer cognitive outcomes...
Uncovering the Mechanism of Potassium Channel Folding and Assembly with Implications for the Molecular Basis of Cardiac Arrhythmia
Project Summary/Abstract Potassium channels are membrane proteins critical for the electrochemical regulation and function of cardiac cells. Many diseases are associated with mutat...
Myeloid-specific IRE1alpha as a mediator of nonalcoholic fatty liver disease
PROJECT SUMMARY/ABSTRACT Alongside the unabating global obesity crisis, there has been a rise in non-alcoholic fatty liver disease (NAFLD), now affecting as many as ~1-in-3 America...
Seizures and Children's Outcomes after Stroke (SCOUTS)
PROJECT SUMMARY/ABSTRACT Epilepsy is one of the common problems that can result after ischemic stroke in a child. Children with post- stroke epilepsy have poorer cognitive outcomes...