Results for Health
130,725 grants found
Showing 126,941 – 126,960 of 130,725 grants for "Health"
Natural killer cells in pulmonary ischemia-reperfusion injury
This is an application for a BLRD CDA-2 award for Dr. Daniel Calabrese, a staff physician at the SFVA and an Assistant Professor in the Division of Pulmonary and Critical Care at t...
Establishing a Novel Instrumental Model for Elucidating Mitochondrial DNA-Associated Dysfunction and Pathogenicity
Project Summary/Abstract The Shao group at Iowa State University aims to leverage their expertise in genetic tool development to assemble a comprehensive mitochondrial genetic tool...
ROS Mechanisms in BAV Aortopathy
PROJECT SUMMARY Ascending aortic aneurysmal disease is a major worldwide health problem. Bicuspid aortic valve (BAV)- associated aortopathy represents the largest subset of affecte...
Pharmacology & ImmunoPathology (PIP) Core
Pharmacology and Immunopathology Core – Hackensack Meridian Health ABSTRACT The pharmacology and ImmunoPathology Shared Resource Core will serve the Projects and the Clinical Core...
Establishing a Novel Instrumental Model for Elucidating Mitochondrial DNA-Associated Dysfunction and Pathogenicity
Project Summary/Abstract The Shao group at Iowa State University aims to leverage their expertise in genetic tool development to assemble a comprehensive mitochondrial genetic tool...
Utilizing Human Brain Organoids to Model the Differential Effects of SCN8A Mutation on Cortex and Hippocampus
Project Summary/Abstract Epilepsy is a severe and debilitating disease and a significant public health concern. Epilepsy is also a disease without a medical cure, and a disease whe...
Genetics & Genomics Training Program
This application is a request for support for the Predoctoral Training Program in Genetics & Genomics at Baylor College of Medicine. This Program started in 1987 and has been f...
Vagal REV-ERB as a Circadian Regulator of Satiation Signaling
Project Summary Obesity is an international epidemic with significant health and economic consequences. Excess caloric intake and dysregulated feeling of hunger/fullness largely co...
Defining mechanisms of perianal fistula inception in African and European ancestry Crohn's disease patients
PROJECT SUMMARY Crohn’s disease (CD) is characterized by progressive, transmural inflammation that can affect any region of the gastrointestinal tract. Penetrating complications, m...
Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants
Project Summary/Abstract There is growing societal and scientific interest in using genomic sequencing (GS) as screening to identify genetic predispositions for disease early in li...
Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants
Project Summary/Abstract There is growing societal and scientific interest in using genomic sequencing (GS) as screening to identify genetic predispositions for disease early in li...
MRI Resource for Physiologic, Metabolic and Anatomic Biomarkers
SUMMARY The importance of biomarkers in clinical practice and regulatory science is difficult to overstate.The ultimate goal for clinical care of the future is to determine the mos...
Ultrasound image-guided treatment of ischemia-reperfusion injury using argon microbubbles
The key health significance of this proposal involves the ultrasound-mediated, image-guided, localized treatment of ischemia reperfusion injury (IRI) in neuronal and cardiac models...
Transcriptional Regulators in Aging Macrophages
As key governors of tissue integrity, macrophages are implicated in many age-related diseases. Macrophages are a plastic myeloid immune cell type found in nearly every tissue of th...
Natural killer cells in pulmonary ischemia-reperfusion injury
This is an application for a BLRD CDA-2 award for Dr. Daniel Calabrese, a staff physician at the SFVA and an Assistant Professor in the Division of Pulmonary and Critical Care at t...
Role of repetitive element transcripts in brain aging and Alzheimer's disease
PROJECT SUMMARY The purpose of this NIH F32 training application is to provide support for Dr. Devin Wahl’s research and training that will prepare him to become an independent inv...
MyGI Diet for Colorectal Cancer Prevention
PROJECT SUMMARY Despite the large body of research that has identified the impact of diet on cancer risk, little has been done to translate these findings to clinical settings. Her...
ROS Mechanisms in BAV Aortopathy
PROJECT SUMMARY Ascending aortic aneurysmal disease is a major worldwide health problem. Bicuspid aortic valve (BAV)- associated aortopathy represents the largest subset of affecte...
Engineering protein-specific proteases: targeting signaling proteins
Project Summary The goal of this supplement application is to successfully re-integrate Dr. Betty Chu into the research community over Years 3 and 4 of the parent R01 award. Dr. Ch...
Chronic Versus Acute Transplantation of Neural Tissues for TBI-Induced Cortical Injuries
PROJECT SUMMARY/ABSTRACT Injury to the cerebral cortex occurs frequently across the spectrum of severity in traumatic brain injury (TBI). No therapies exist to counter the neurolog...