Results for Health
130,725 grants found
Showing 126,981 – 127,000 of 130,725 grants for "Health"
The discovery and validation of biomarkers of renal epithelial senescence in the human kidney.
Chronic kidney disease (CKD) is common; it affects 8% of the UK population. It is important because patients with kidney disease are at higher risk of death, particularly from hear...
Behavioral and Pharmacological Treatments to Enhance Weight Outcomes after Metabolic and Bariatric Surgery
Project Summary. Rates of obesity and severe obesity are expected to continue to rise to alarming levels. By 2030, over 51% of adults in the US are expected to have obesity with a...
Post-Discharge Nephrology Follow-up for Improved Outcomes
PROJECT SUMMARY/ABSTRACT Acute kidney injury (AKI) is a common complication experienced by roughly 20% of adult patients during hospitalization.AKI is associated with long-term adv...
Collaborative Research: Examining the Role of Compensation and Other Factors for Retention of Teachers in High-need Schools
This project aims to serve the national need of retaining effective STEM teachers in high-need schools. The research team seeks to understand what induces STEM teachers to continue...
CAREER: Elucidating the Role of Collective Cell-Matrix Interactions in the Mechanobiology of Airway Narrowing
This Faculty Early Career Development (CAREER) award aims to reveal how physical forces enable the airway smooth muscle and the surrounding tissue to work together to detect inhale...
Therapeutics targeting TDP-43 to treat Alzheimer's disease and related disorders
TDP-43 is a mixed proteinopapthy in Alzheimer’s disease (AD), AD-TDP, based on substantial epidemiological data correlating TDP-43 inclusions with cognitive decline in AD patients....
Real-Time Haptic Performance Feedback for Model-Based Surgical Skill Training
The goal of this project is to make endovascular surgical training in virtual reality-based simulators faster, more consistent, and more efficacious by adding online vibrotactile (...
Collaborative Research: Examining the Role of Compensation and Other Factors for Retention of Teachers in High-need Schools
This project aims to serve the national need of retaining effective STEM teachers in high-need schools. The research team seeks to understand what induces STEM teachers to continue...
Multi-color optical voltage imaging of neural activity in behaving animals
Abstract Groundbreaking work within the NIH BRAIN Initiative has revealed many new types of neurons and their genetic signatures. The dividends from this research will include soph...
Targeting Bcl-2 Family Proteins to Facilitate Fibroblast Apoptosis and Promote the Resolution of Pulmonary Fibrosis
Project Summary/Abstract This project aims to understand and control the anti-apoptotic mechanisms employed by fibroblasts to evade apoptosis during the fibrotic process. Pulmonary...
Targeting Bcl-2 Family Proteins to Facilitate Fibroblast Apoptosis and Promote the Resolution of Pulmonary Fibrosis
Project Summary/Abstract This project aims to understand and control the anti-apoptotic mechanisms employed by fibroblasts to evade apoptosis during the fibrotic process. Pulmonary...
Impact of early-life perturbations on pediatric microbiome maturation
ABSTRACT During the first 3-years of life (YOL) the infant gut microbiome (GM) rapidly diversifies both in structure and function, concomitant with dietary and environmental transi...
Targeting Bcl-2 Family Proteins to Facilitate Fibroblast Apoptosis and Promote the Resolution of Pulmonary Fibrosis
Project Summary/Abstract This project aims to understand and control the anti-apoptotic mechanisms employed by fibroblasts to evade apoptosis during the fibrotic process. Pulmonary...
Impact of early-life perturbations on pediatric microbiome maturation
ABSTRACT During the first 3-years of life (YOL) the infant gut microbiome (GM) rapidly diversifies both in structure and function, concomitant with dietary and environmental transi...
Impact of early-life perturbations on pediatric microbiome maturation
ABSTRACT During the first 3-years of life (YOL) the infant gut microbiome (GM) rapidly diversifies both in structure and function, concomitant with dietary and environmental transi...
Serological Biomarkers for Coccidioidomycosis
PROJECT SUMMARY As of 2017, coccidioidomycosis (Cocci) also known as Valley Fever (VF) was designated a reportable disease in 22 states (1).The majority of the cases in the US occu...
Disseminable Evidence-Based Treatment for the Dental Office: Virtual Exposure Tools for Dental Fear - neVR Fear the Dentist
PROJECT SUMMARY/ABSTRACT Each year over 20 million adults with moderate fear and over 14 million adults with severe fear visit the dentist.Because fear portends poor future oral he...
Device for Preservation of Cell Free RNA in Saliva
ABSTRACT Early detection is critical to cancer mortality reductions, and yet the breast imaging clinic visits required for these life-saving early detection programs are inaccessib...
Serological Biomarkers for Coccidioidomycosis
PROJECT SUMMARY As of 2017, coccidioidomycosis (Cocci) also known as Valley Fever (VF) was designated a reportable disease in 22 states (1). The majority of the cases in the US occ...
Targeting lysosome/RPE heterogeneity in AMD pathobiology as a novel therapy
SUMMARY: Vision loss from age-related macular degeneration (AMD) is a major, expanding problem due to the aging population.While treatment is available for intermediate AMD and the...