Results for Health
130,725 grants found
Showing 127,081 – 127,100 of 130,725 grants for "Health"
Complexity and the Wound Healing Response
Project Summary The ability to heal is essential for human health. The remarkable wound healing capacity of humans (and indeed of all animals) is a complicated process. Genomic stu...
Mechanism of chromatin accessibility, 3D chromosome organization, and their functions in gene regulation
Project Abstract The overall theme of my research program is to understand the formation mechanism of chromatin structure and its role in gene regulation. We plan to address this p...
Mechanism and dynamics of islet GABA signaling
Gamma-aminobutyric acid (GABA) is a potent neurotransmitter produced in the islet at levels as high as in the brain.While the function of GABA in the nervous system is well-underst...
Elucidating the role and mechanisms by which collagenase producing intestinal bacteria promote colorectal cancer recurrence and metastasis following surgery.
PROJECT SUMMARY / ABSTRACT Colorectal cancer (CRC) is a major health concern with nearly 2-million new cases of CRC diagnosed worldwide in 2019. While surgical resection of the pri...
lluminating the biochemistry of zinc and RNA in live cells
Project Summary Zinc (Zn2+) is the second most abundant transition metal in mammals after iron. There are over two thousand proteins encoded by the human genome that contain zinc b...
Novel Integrative Approach for the Early Detection of Lung Cancer using Repeated Measures
PROJECT SUMMARY Early detection of lung cancer among asymptomatic individuals is a priority for reducing mortality of the number one cancer killer worldwide. Most lung cancers are...
Commensal-specific T cell function in skin wound repair
PROJECT SUMMARY Our understanding of immunity largely stems from models of infection with pathogenic microbes.However, the vast majority of microbial-immune encounters occur as a s...
Evaluating the role of P53 pathways in malaria
Project Summary/Abstract Malaria caused by the Plasmodium parasite remains a global health threat, affecting ~200 million people and leading to more than 400,000 deaths per year.Un...
Mobile Ecological Momentary Diet Assessment: A Low Burden, Ecologically-Valid Approach to Measuring Dietary Intake in Near-Real Time
ABSTRACT The excessive intake of saturated fat and added sugars has been identified as a leading cause of premature mortality among adults in the U.S. contributing to approximately...
Regulation of spore peptidoglycan modification
Dr. Gabrielle Valles recently received her Ph.D. from the University of Connecticut, where she used NMR spectroscopy and X-ray crystallography to study the structure and function o...
Structure, Mechanism and Interactions of Type IA Topoisomerases
Project Summary/Abstract Type IA topoisomerases are ubiquitous in the three kingdoms of life, and play critically important roles in maintaining proper DNA topology during the vita...
Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer Risk
ABSTRACT.Colorectal cancer (CRC) is associated with multiple risk factors including, obesity, low fiber diets, and diets high in animal protein and saturated fat (SFat).African Ame...
An ounce of prevention: stopping menopausal bone loss before it starts
Summary The aphorism ?an ounce of prevention is worth a pound of cure? very much applies to postmenopausal osteoporosis. Immediately following menopause, bone loss rates can reach...
An ounce of prevention: stopping menopausal bone loss before it starts
Summary The aphorism “an ounce of prevention is worth a pound of cure” very much applies to postmenopausal osteoporosis. Immediately following menopause, bone loss rates can reach...
An automated, scalable, and rapid AST system for Gonorrhea STIs
Gonorrhea is a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae (NG) that infects the urogenital, anorectal and pharyngeal tracts in humans. In 20...
Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer Risk
ABSTRACT. Colorectal cancer (CRC) is associated with multiple risk factors including, obesity, low fiber diets, and diets high in animal protein and saturated fat (SFat). African A...
Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer Risk
ABSTRACT. Colorectal cancer (CRC) is associated with multiple risk factors including, obesity, low fiber diets, and diets high in animal protein and saturated fat (SFat). African A...
Transmission and evolution of a persistent pathogen: anthrax infection dynamics comparing two natural systems
Anthrax is a globally distributed disease of wildlife, livestock, and humans. Successful prediction of and response to outbreaks of anthrax is limited by a lack of understanding of...
SCC-Civic-PG Track A:Flexible Mobility-as-a-Service to Improve Post-Pandemic Regional Sustainability
This project's vision is to encourage sustainable mobility habits that can take advantage of new mobility services. There are enormous debates over whether emerging mobility s...
ELECTRONIC CIGARETTE VAPING & VASCULAR SEQUELAE IN THE UTERUS DURING PREGNANCY.
ELECTRONIC CIGARETTE VAPING & VASCULAR SEQUELAE IN THE UTERUS DURING PREGNANCY Despite serious pregnancy complications, 50% of women who use tobacco products will continue to d...