Results for Health
130,725 grants found
Showing 127,141 – 127,160 of 130,725 grants for "Health"
Mechanism and dynamics of islet GABA signaling
Gamma-aminobutyric acid (GABA) is a potent neurotransmitter produced in the islet at levels as high as in the brain.While the function of GABA in the nervous system is well-underst...
lluminating the biochemistry of zinc and RNA in live cells
Project Summary Zinc (Zn2+) is the second most abundant transition metal in mammals after iron. There are over two thousand proteins encoded by the human genome that contain zinc b...
Enabling Mass Spectrometry Analysis of the Sulfoproteome
Project Summary Tyrosine O-sulfation, i.e., transfer of a sulfonate group to tyrosine amino acid residues in proteins, is a widespread posttranslational modification (PTM) in eukar...
Medicating distress: Use of psychotropic medications among patients with dementia receiving hospice care
ABSTRACT The goal of this Mentored Career Development Award is to prepare Dr. Lauren Gerlach for a career as an independent investigator focused on measuring and improving the qual...
Neurodevelopment after postnatal Zika virus infection in infant macaques
PROJECT SUMMARY / ABSTRACT Intense research has focused on the neurologic effects of prenatal Zika virus (ZIKV) infection; however, the consequences of postnatal infection early in...
The role of Bik in the replication and severity of influenza A virus
Influenza A virus (IAV) is responsible for seasonal epidemics that results in severe respiratory illness and deaths worldwide, costing billions of dollars annually in the U.S. alon...
Population-Targeted Risk Prediction to Guide Breast Cancer Screening in Cameroon
Project Summary/Abstract: As cancer becomes an increasingly important cause of mortality in sub-Saharan Africa, nations must improve their capacity to diagnose and treat the malign...
Complexity and the Wound Healing Response
Project Summary The ability to heal is essential for human health. The remarkable wound healing capacity of humans (and indeed of all animals) is a complicated process. Genomic stu...
Ecological management to benefit ecosystem services and sustainable production in smallholder oil palm systems in Malaysia and Indonesia
This project will build on a large-scale experimental project, based within large industrial oil palm plantations in Riau, Indonesia, that investigated the impact of varying herbic...
CAREER: How streamflow ages vary downstream along river courses
The time that rain takes to move through a landscape and enter a river regulates contaminant transport and the movement of nutrients along streams. This time is influenced by the c...
Role of African-centric TP53 variant in higher H. pylori prevalence in African Americans
Project Summary African Americans have a 6-fold higher H. pylori (Hp) infection than the non-Hispanic white population; however, underlying gene(s) for this disparity remain elusiv...
Role of African-centric TP53 variant in higher H. pylori prevalence in African Americans
Project Summary African Americans have a 6-fold higher H. pylori (Hp) infection than the non-Hispanic white population; however, underlying gene(s) for this disparity remain elusiv...
Role of African-centric TP53 variant in higher H. pylori prevalence in African Americans
Project Summary African Americans have a 6-fold higher H. pylori (Hp) infection than the non-Hispanic white population; however, underlying gene(s) for this disparity remain elusiv...
Behavioral economic and wellness-based approaches for reducing alcohol use and consequences among diverse non-student emerging adults
Brief alcohol interventions (BAI) are among the most cost-effective preventive care measures available and the evaluation of these interventions with high-risk and difficult-to-rea...
Elucidating the causal associations underlying Alzheimer's disease
Project Summary Alzheimer?s disease (AD) is a global crisis facing the aging population and society as a whole.With the number of people living with AD predicted to rise dramatical...
Genetic Predictors of Prostate Cancer Survival
Prostate cancer (PC) has a very heterogenous clinical course. Many men have an indolent PC that can be safely watched for years without progression. Alternatively, other men have a...
Identifying the Cognitive, Psychological, and Neuroimaging Signatures of Head Trauma in Female Survivors of Intimate Partner Violence
Intimate partner violence (IPV), the physical violence, sexual violence, psychological aggression, or stalking by a current or former intimate partner, is a significant public heal...
Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer Risk
ABSTRACT. Colorectal cancer (CRC) is associated with multiple risk factors including, obesity, low fiber diets, and diets high in animal protein and saturated fat (SFat). African A...
An automated, scalable, and rapid AST system for Gonorrhea STIs
Gonorrhea is a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae (NG) that infects the urogenital, anorectal and pharyngeal tracts in humans. In 20...
Machine learning methods for studying the trajectories of young offenders in administrative data
Administrative data has the potential to open new and invaluable research opportunities to better understand societal phenomena and support evidence-based policy-making. One resear...